Evaluation of Stroke Care Delivery: 12-Month Experience of a Tertiary Stroke Center in Central Asia


Grigolashvili M. Klyuyev D. Kasatkin D. Battakova S. Shayakhmetova Y. Beisembayeva M. Muratbekova S. Koshelyuk A. Baituyak Y. Turkevich I. Dey A.
2025John Wiley and Sons Ltd

International Journal of Clinical Practice
2025#2025Issue 1

The present study is a retrospective analysis of the activities of a tertiary stroke center (SC) operating on the basis of Akzhan Clinic in Karaganda Region during the year 2024. The primary objective of this study was to examine the epidemiological features, the structure of stroke morbidity, and the efficacy of thrombolytic therapy (TLT) in patients with ischemic stroke (IS). The study included data from a total of 585 patients, out of which 437 had been hospitalized with acute cerebrovascular disorders, and 104 of these patients had received TLT for IS. The analysis revealed a high level of utilization of TLT (23.8%), which was significantly higher than the average regional and national figures, owing to the efficient organization of prehospital and in-hospital stages, availability of skilled personnel, and a state-of-the-art technical infrastructure. Additionally, mechanical thrombectomy (MT) was performed in 100 instances, further confirming the high level of adoption of advanced treatment modalities. The proportion of hemorrhagic transformations (7.69%) and mortality (6.7%) was comparable to or lower than international benchmarks. The results demonstrate the high effectiveness of the performance of the SC “Akzhan” and the need for the further expansion of similar facilities in order to improve the accessibility and quality of stroke treatment in Kazakhstan. Copyright

epidemiology , ischemic stroke , Karaganda , Kazakhstan , mechanical thrombectomy , regional stroke center , thrombolytic therapy

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Department of Neurology, Psychiatry and Rehabilitation, Karaganda Medical University, Karaganda, Kazakhstan
Institute of Life Sciences, Karaganda Medical University, Karaganda, Kazakhstan
Department of Neurology, Yaroslavl State Medical University, Yaroslavl, Russian Federation
Stroke Department, «Akzhan» LLP, Karaganda, Kazakhstan

Department of Neurology
Institute of Life Sciences
Department of Neurology
Stroke Department

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