Assessment of the quality of life of women in the menopausal transition
Grebennikova G.A. Jaimbetova A.P. Roslyakova A.V.
2024Kaz Med Print LLP
Reproductive Medicine (Central Asia)
2024#2024Issue 392 - 100 pp.
Relevance: The frequency of menopausal symptoms that reduce womens quality of life reaches 80%. In international recommendations, improving quality of life is a principle in correcting menopausal disorders. It is one of the reasons for going to the doctor. Hormone replacement therapy is an effective treatment for climacteric disorders that support health and improve quality of life. The study aimed to assess the nature of the symptoms of menopausal syndrome and the quality of life of women using menopausal hormone therapy during menopausal transition. Materials and Methods: The severity of vegetative, metabolic, and psycho-emotional symptoms (15) was assessed using the Kuperman scale modified by E.V. Uvarova (4-point scale). Quality was assessed using the SF-36 questionnaire (5-point scale). The data were collected in four stages: before inclusion in the group, at 1, 3, and 6 months after the prescription of menopausal hormone therapy (estradiol valerate – 2 mg/estradiol valerate – 2 mg; levonorgestrel – 0.15 mg). Results: The quality of life before inclusion in the group was assessed at 2.7 ± 0.17 points, with an increase to 4.4 ± 0.21 after 6 months of taking the drug. At the end of the study, 96.3% of patients rated their health as good, while before their inclusion in the group as mediocre (65.6%) and 31.8%-bad. Before hormone replacement therapy, 1/3 of patients had severe menopausal syndrome, with neuro-autonomic (26.4%) and psycho-emotional symptoms (42.3%). The influence and frequency of neurovegetative symptoms decreased by the end of the first month. A positive result for psycho-emotional symptoms is six months after the start of therapy. Conclusion: The correlation between taking the drug and reducing the severity of symptoms, improving the quality of life, and increasing satisfaction with the state of health speaks about the effectiveness of hormone replacement therapy.
menopausal hormone therapy , menopausal syndrome , quality of life assessment
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Kazakhstan Association for Sexual and Reproductive Health (KMPA), Almaty, Kazakhstan
Institute of Reproductive Medicine, Almaty, Kazakhstan
Kazakhstan Association for Sexual and Reproductive Health (KMPA)
Institute of Reproductive Medicine
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