Neurotransmitters Regulation and Food Intake: The Role of Dietary Sources in Neurotransmission


Gasmi A. Nasreen A. Menzel A. Gasmi Benahmed A. Pivina L. Noor S. Peana M. Chirumbolo S. Bjørklund G.
January 2023MDPI

Molecules
2023#28Issue 1

Neurotransmitters (NTs) are biologically active chemicals, which mediate the electrochemical transmission between neurons. NTs control numerous organic functions particularly crucial for life, including movement, emotional responses, and the physical ability to feel pleasure and pain. These molecules are synthesized from simple, very common precursors. Many types of NTs have both excitatory and inhibitory effects. Neurotransmitters’ imbalance can cause many diseases and disorders, such as Parkinson’s disease, depression, insomnia, increased anxiety, memory loss, etc. Natural food sources containing NTs and/or their precursors would be a potential option to help maintain the balance of NTs to prevent brain and psychiatric disorders. The level of NTs could be influenced, therefore, by targeting dietary habits and nutritional regimens. The progressive implementation of nutritional approaches in clinical practice has made it necessary to infer more about some of the nutritional NTs in neuropsychiatry. However, the importance of the intake of nutritional NTs requires further understanding, since there are no prior significant studies about their bioavailability, clinical significance, and effects on nerve cells. Interventional strategies supported by evidence should be encouraged.

dietary supplements , food , health effects , nervous system , neurotransmitters , precursors

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Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée, Villeurbanne, 69100, France
Department of Physiology, King Edward Medical University, Lahore, 54000, Pakistan
Laboratoires Réunis, 38, Rue Hiehl, Junglinster, L-6131, Luxembourg
Académie Internationale de Médecine Dentaire Intégrative, Paris, 75000, France
Department of Neurology, Ophthalmology and Otolaryngology, Semey Medical University, Semey, 071400, Kazakhstan
CONEM Kazakhstan Environmental Health and Safety Research Group, Semey Medical University, Semey, 071400, Kazakhstan
Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, 60800, Pakistan
Department of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, Via Vienna 2, Sassari, 07100, Italy
Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, 37134, Italy
CONEM Scientific Secretary, Strada Le Grazie 9, Verona, 37134, Italy
Council for Nutritional and Environmental Medicine, Toften 24, Mo i Rana, 8610, Norway

Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée
Department of Physiology
Laboratoires Réunis
Académie Internationale de Médecine Dentaire Intégrative
Department of Neurology
CONEM Kazakhstan Environmental Health and Safety Research Group
Institute of Molecular Biology and Biotechnology
Department of Chemical
Department of Neurosciences
CONEM Scientific Secretary
Council for Nutritional and Environmental Medicine

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