Crystal structures and antimicrobial and antioxidant activities of phosphonium compounds containing 3,5-di-tert-butyl-4-hydroxybenzyl fragment
Galkina I.V. Andriyashin V.V. Ziyatdinova G.K. Romanov S.R. Egorova S.N. Vorob’eva N.V. Shulaeva M.P. Litvinov I.A. Abzhalelov B.B. Kuzhamberdieva S.Z. Bakhtiyarova Y.V.
March 2024Springer
Russian Chemical Bulletin
2024#73Issue 3695 - 703 pp.
The antimicrobial and antioxidant properties of a series of organophosphorous compounds containing the 3,5-di-tert-butyl-4-hydroxybenzyl fragment were studied. As revealed in biological activity assays, the majority of the compounds simultaneously possesses high antibacterial and fungicidal activities against pathogenic and arbitrarily pathogenic human and animal microflora. The influence of the substituents at the phosphonate phosphorus atom and the number of fragments of sterically hindered phenol on the antioxidant capacity of the studied compounds was found. In the case of methoxyl substituents at the phosphonate phosphorus atom, the antioxidant activity decreases sharply compared to the initial antioxidant, ionol (2,6-di-tert-butylphenol), whereas the phenoxyl substituents at the phosphorus atom sharply increase the antioxidant activity of the studied salts.
2,6-di-tert-butyl-4-hydroxybenzyl fragment , anti-oxidant activity , antimicrobial activity , coulometric titration , electrogenerated bromine
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Kazan (Volga Region) Federal University, 18 ul. Kremlevskaya, Kazan, 420008, Russian Federation
Kazan State Medical University, 49 ul. Butlerova, Kazan, 420012, Russian Federation
Kazan State Medical Academy, 11 ul. Mushtari, Kazan, 420012, Russian Federation
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”, 8 ul. Arbuzova, Kazan, 420088, Russian Federation
Kyzylorda University named after Korkyt Ata, 29a ul. Aiteke Bi, Kyzylorda, 120014, Kazakhstan
Kazan (Volga Region) Federal University
Kazan State Medical University
Kazan State Medical Academy
A. E. Arbuzov Institute of Organic and Physical Chemistry
Kyzylorda University named after Korkyt Ata
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