Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019
Galiyeva D. Gusmanov A. Sakko Y. Issanov A. Atageldiyeva K. Kadyrzhanuly K. Nurpeissova A. Rakhimzhanova M. Durmanova A. Sarria-Santamera A. Gaipov A.
December 2022BioMed Central Ltd
BMC Endocrine Disorders
2022#22Issue 1
Background: We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) and to investigate demographic factors and comorbidities associated with all-cause mortality by aggregating and utilizing large-scale administrative healthcare data from the Unified National Electronic Health System (UNEHS) of Kazakhstan for 2014–2019 years period. Methods: A total of 475,539 individuals were included in the analyses. The median years of follow-up for Type 1 DM patients accounted for 4.7 years and 4.5 years in Type 2 DM patients. We used Kaplan-Meier and log-rank test to calculate failure function and differences in survival by age, sex, ethnicity, and comorbidities with all-cause mortality for Type 1 and Type 2 DM. Cox proportional hazards regression analysis was used to obtain crude and adjusted hazard ratios. Results: Prevalence of Type 1 and Type 2 DM increased 1.7 times from 2014 to 2019. Mortality of Type 1 and Type 2 DM also increased 4 times and 6 times from 2014 to 2019, respectively. Male sex, older age and Kazakh ethnicity were associated with a higher risk of all-cause death compared to females, younger age and other nationalities than Kazakh in patients with Type 1 and Type 2 DM. Coronary artery disease, diabetic nephropathy, stroke, amputations and neoplasms were associated with a higher risk of all-cause death. Conclusion: The prevalence and mortality rate of Type 1 and Type 2 DM increased during the years 2014–2019 in Kazakhstan. Male sex, older age and Kazakh ethnicity were associated with a higher risk of all-cause death compared to females, younger age and other nationalities than Kazakh. Coronary artery disease, diabetic nephropathy, stroke, amputations and neoplasms were associated with a higher risk of all-cause death.
Comorbidities , Diabetes , Epidemiology , Mortality , Survival
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Department of Medicine, School of Medicine, Nazarbayev University, Kerey and Zhanibek street #5/1, Nur-Sultan, 010000, Kazakhstan
School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada
Clinical Academic Department of Internal Medicine, University Medical Center, Nur-Sultan, Kazakhstan
Department of Medical Information Analysis of Outpatient and Polyclinic Care, Republican Center of Electronic Healthcare, Nur-Sultan, Kazakhstan
Clinical Academic Department of Pediatrics, University Medical Center, Nur-Sultan, Kazakhstan
Department of Medicine
School of Population and Public Health
Clinical Academic Department of Internal Medicine
Department of Medical Information Analysis of Outpatient and Polyclinic Care
Clinical Academic Department of Pediatrics
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