Future and the past of polymeric antioxidants
Filippov S.K. Domnina N. Voleva V.
July 2021John Wiley and Sons Ltd
Polymers for Advanced Technologies
2021#32Issue 72655 - 2668 pp.
Hybrid macromolecular antioxidants has evolved into a mature research field last three decades. The main concept of this area was to design polymer conjugates that combine in one structure the hydrophilic properties of a polymer backbone and biological efficiency of hydrophobic antioxidants. Over the years, the understanding of different aspects of such approach has grown. In general, meticulous selection of each component is essential to obtain the conjugate with required properties. This review overview a plethora of hybrid macromolecular antioxidants synthesized over the last 20 years, together with the discussion their physicochemical properties and application for biomedical purposes.
amphiphilic polymers , hybrid macromolecular antioxidants , mechanism of antioxidant activity , sterically hindered phenols , structure
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Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Turku, Finland
Department of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, Kazakhstan
Department of Macromolecular Compounds Chemistry, St. Petersburg State University, Institute of Chemistry, St. Petersburg, Russian Federation
Department of Antioxidant Chemistry, Emanuel Institute of Biochemical Physics of Russian Academy of Sciences, Moscow, Russian Federation
Pharmaceutical Sciences Laboratory
Department of Chemistry and Chemical Technology
Department of Macromolecular Compounds Chemistry
Department of Antioxidant Chemistry
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