3D structured capillary cell suspensions aided by aqueous two-phase systems


Dyab A.K.F. Paunov V.N.
8 October 2024Royal Society of Chemistry

Journal of Materials Chemistry B
2024#12Issue 4010215 - 10220 pp.

We report a facile technique for 3D structuring of living cells by forming capillary cell suspensions based on an aqueous two-phase system (ATPS) of polyethylene glycol (PEG) and dextran (DEX) solutions. We demonstrate the formation of water-in-water (DEX-in-PEG) capillary bridges using concentrated suspensions of yeast cells which show enhanced rheological properties and distinctive 3D patterns. Capillary structured cell suspensions can potentially find applications in novel ways of 3D cell culturing, instant tissue engineering and many biomedical investigations.



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Department of Chemistry, Nazarbayev University, Kabanbay Batyr 53, Astana, 010000, Kazakhstan
Colloids & Advanced Materials Group, Chemistry Department, Faculty of Science, Minia University, Minia, 61519, Egypt

Department of Chemistry
Colloids & Advanced Materials Group

10 лет помогаем публиковать статьи Международный издатель

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