Drug-Resistant Tuberculosis, Georgia, Kazakhstan, Kyrgyzstan, Moldova, and Ukraine, 2017-2022


Dahl V.N. Butova T. Rosenthal A. Grinev A. Gabrielian A. Vashakidze S. Shubladze N. Toxanbayeva B. Chingissova L. Crudu V. Chesov D. Kalmambetova G. Saparova G. Wejse C.M. Butov D.
April 2024Centers for Disease Control and Prevention (CDC)

Emerging Infectious Diseases
2024#30Issue 4831 - 833 pp.

In 2021, the World Health Organization recommended new extensively drug-resistant (XDR) and pre-XDR tuberculosis (TB) definitions. In a recent cohort of TB patients in Eastern Europe, we show that XDR TB as currently defined is associated with exceptionally poor treatment outcomes, considerably worse than for the former definition (31% vs. 54% treatment success).



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Aarhus University Hospital, Aarhus, Denmark
Merefa Central District Hospital, Merefra, Ukraine
National Institutes of Health, Bethesda, MD, United States
National Center for Tuberculosis and Lung Diseases, Tbilisi, Georgia
National Scientific Center of Phthisiopulmonology, Almaty, Kazakhstan
Institute of Phthisiopneumology, Chisinau, Moldova
State University of Medicine and Pharmacy, Chișinău, Moldova
National TB Program, Bishkek, Kyrgyzstan
Kharkiv National Medical University, Kharkiv, Ukraine

Aarhus University Hospital
Merefa Central District Hospital
National Institutes of Health
National Center for Tuberculosis and Lung Diseases
National Scientific Center of Phthisiopulmonology
Institute of Phthisiopneumology
State University of Medicine and Pharmacy
National TB Program
Kharkiv National Medical University

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