Vital Signs: Progress Toward Eliminating HIV as a Global Public Health Threat Through Scale-Up of Antiretroviral Therapy and Health System Strengthening Supported by the U.S. President’s Emergency Plan for AIDS Relief — Worldwide, 2004–2022
Chun H.M. Dirlikov E. Cox M.H. Sherlock M.W. Obeng-Aduasare Y. Sato K. Voetsch A.C. Ater A.D. Romano E.R. Tomlinson H. Modi S. Achrekar A. Nkengasong J. Agolory S. Amann J. Baack B. Behel S. Date A. Hanson J. Killam W.P. Patel H. Patel S. Pati R. Porter L. Warner A. Wuhib T. Zeh C. Silva Santelli A.C.F.E. Guevara G. Morales R.E. Ekra A.K. Kitenge F. Bonilla L. Mazibuko S. Damena T. Joseph P. Upadhyaya S. Aitmagambetova I. Mwangi J. Usmanova N. Xaymounvong D. Asiimwe M. Alice M. Masamha G.J. Mutandi G. Odafe S. Romel L. Musoni C. Mogashoa M. Bolo A. Nabidzhonov A. Mgomella G. Lolekha R. Alamo-Talisuna S. Podolchak N. Nguyen C.K. Quaye S. Mwila A. Nyika P.
2023Department of Health and Human Services
Morbidity and Mortality Weekly Report
2023#72Issue 12317 - 324 pp.
Introduction: In 2004, the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), with CDC as a major U.S. government implementing agency, began providing HIV antiretroviral therapy (ART) worldwide. Through suppression of HIV viral load, effective ART reduces morbidity and mortality among persons with HIV infection and prevents vertical and sexual transmission. Methods: To describe program impact, data were analyzed from all PEPFAR programs and from six countries that have conducted nationally representative Population-based HIV Impact Assessment (PHIA) surveys, including PEPFAR programmatic data on the number of persons with HIV infection receiving PEPFAR-supported ART (2004–2022), rates of viral load coverage (the proportion of eligible persons with HIV infection who received a viral load test) and viral load suppression (proportion of persons who received a viral load test with <1,000 HIV copies per mL of blood) (2015–2022), and population viral load suppression rates in six countries that had two PHIA surveys conducted during 2015–2021. To assess health system strengthening, data on workforce and laboratory systems were analyzed. Results: By September 2022, approximately 20 million persons with HIV infection in 54 countries were receiving PEPFAR-supported ART (62% CDC-supported); this number increased 300-fold from the 66,550 reported in September 2004. During 2015–2022, viral load coverage more than tripled, from 24% to 80%, and viral load suppression increased from 80% to 95%. Despite increases in viral load suppression rates and health system strengthening investments, variability exists in viral load coverage among some subpopulations (children aged <10 years, males, pregnant women, men who have sex with men [MSM], persons in prisons and other closed settings [persons in prisons], and transgender persons) and in viral load suppression among other subpopulations (pregnant and breastfeeding women, persons in prisons, and persons aged <20 years). Conclusions and implications for public health practice: Since 2004, PEPFAR has scaled up effective ART to approximately 20 million persons with HIV infection in 54 countries. To eliminate HIV as a global public health threat, achievements must be sustained and expanded to reach all subpopulations. CDC and PEPFAR remain committed to tackling HIV while strengthening public health systems and global health security.
Text of the article Перейти на текст статьи
Division for Global HIV and TB, Center for Global Health, CDC, United States
Office of the U.S. Global AIDS Coordinator and Health Diplomacy, U.S. Department of State, Washington, DC, United States
CDC Brazil Country Office, Brazil
Caribbean Regional Office, Jamaica
CDC Central America Regional Office, Costa Rica
CDC Côte d’Ivoire Country Office, Cote dIvoire
CDC Democratic Republic, The Congo Country Office, Democratic Republic Congo
CDC Dominican Republic Country Office, Democratic Republic Congo
CDC Eswatini Country Office, Swaziland
Ethiopia Country Office, Ethiopia
CDC Haiti Country Office, Haiti
CDC India Country Office, India
CDC Kazakhstan Country Office, Kazakhstan
CDC Kenya Country Office, Kazakhstan
CDC Kyrgzstan Country Office, Kyrgyzstan
CDC Laos Country Office, Laos
CDC Lesotho Country Office, Lesotho
CDC Malawi Country Office, Malawi
CDC Mozambique Country Office, Mozambique
CDC Namibia Country Office, Namibia
CDC Nigeria Country Office, Nigeria
CDC Philippines Country Office, Philippines
CDC Rwanda Country Office, Rwanda
CDC South Africa Country Office, South Africa
CDC South Sudan Country Office, South Sudan
CDC Tajikistan Country Office, Tajikistan
CDC Tanzania Country Office, Tanzania
CDC Thailand Country Office, Thailand
CDC Uganda Country Office, Uganda
CDC Ukraine Country Office, Ukraine
CDC Vietnam Country Office, Viet Nam
CDC West Africa Regional Program Country Office, Sierra Leone
CDC Zambia Country Office, Zambia
CDC Zimbabwe Country Office, Zimbabwe
Division for Global HIV and TB
Office of the U.S. Global AIDS Coordinator and Health Diplomacy
CDC Brazil Country Office
Caribbean Regional Office
CDC Central America Regional Office
CDC Côte d’Ivoire Country Office
CDC Democratic Republic
CDC Dominican Republic Country Office
CDC Eswatini Country Office
Ethiopia Country Office
CDC Haiti Country Office
CDC India Country Office
CDC Kazakhstan Country Office
CDC Kenya Country Office
CDC Kyrgzstan Country Office
CDC Laos Country Office
CDC Lesotho Country Office
CDC Malawi Country Office
CDC Mozambique Country Office
CDC Namibia Country Office
CDC Nigeria Country Office
CDC Philippines Country Office
CDC Rwanda Country Office
CDC South Africa Country Office
CDC South Sudan Country Office
CDC Tajikistan Country Office
CDC Tanzania Country Office
CDC Thailand Country Office
CDC Uganda Country Office
CDC Ukraine Country Office
CDC Vietnam Country Office
CDC West Africa Regional Program Country Office
CDC Zambia Country Office
CDC Zimbabwe Country Office
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026