Trends in the cytogenetic and immunologic status of healthy persons; Kazakhstan, 2007–2022
Cherednichenko O. Demchenko G. Kapysheva U. Bakhtiyarova S. Pilyugina A. Azizbekova D. Kozhaniyazova U. Zhaksymov B.
October 2024Elsevier B.V.
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
2024#899
Environmental pollution can affect immune health and genome stability. We have studied the immunological and cytogenetic status of healthy urban (Almaty City, which has high levels of air pollution) and rural residents of southern Kazakhstan, over the past 15 years. Differences between the groups in plasma immunoglobulin levels and chromosomal aberration frequencies were noted. Over the 15-year study period, decreases of immunoglobulin levels and increases of chromosomal aberration frequencies were observed and correlated with place of residence and ecological status of the region of residence; both ecological deterioration and the coronavirus pandemic are likely to have had negative effects.
Chromosome aberrations , Ecology , Immunity , Immunoglobulins
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Laboratory of Genetic Monitoring, Institute of Genetics and Physiology, Almaty, Kazakhstan
Laboratory of Physiology of the Lymphatic System, Institute of Genetics and Physiology, Almaty, Kazakhstan
Laboratory of Environmental Physiology of Humans and Animals, Institute of Genetics and Physiology, Almaty, Kazakhstan
Laboratory of Genetic Monitoring
Laboratory of Physiology of the Lymphatic System
Laboratory of Environmental Physiology of Humans and Animals
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