Burden of non-communicable disease studies in Europe: a systematic review of data sources and methodological choices
Charalampous P. Gorasso V. Plass D. Pires S.M. Von Der Lippe E. Mereke A. Idavain J. Kissimova-Skarbek K. Morgado J.N. Ngwa C.H. Noguer I. Padron-Monedero A. Santi-Cano M.J. Sarmiento R. Devleesschauwer B. Haagsma J.A. Ádám B. Alkerwi A. Bikbov B. Bølling A.K. Breitner S. Cuschieri S. Dahm C.C. Eikemo T.A. Fischer F. Freitas A. García-González J.M. Gazzelloni F. Gissler M. Hengl B. Hynds P. Isola G. Jakobsen L.S. Kabir Z. Knudsen A.K. Konar N.M. Ladeira C. Liew A. Majer M. Mechili E.A. Mevsim V. Milicevic M.S. Mitchell L. Monasta L. Mondello S. Nena E. Ng E.S.W. Niranjan V. OCaoimh R. ODonovan M.R. Ortiz A. Pallari E. Petrou P. Ortiz M.R. Riva S. Samouda H. Santos J.V. Adi Santoso C.M. Schmitt T. Skempes D. Sousa A.C. Stevanovic A. Terzic G.S.N. Terzic-Supic Z. Todorovic J. Tozija F. Unim B. Van Wilder L. Varga O. Violante F.S. Wyper G.M.A.
1 April 2022Oxford University Press
European Journal of Public Health
2022#32Issue 2289 - 296 pp.
Background: Assessment of disability-adjusted life years (DALYs) resulting from non-communicable diseases (NCDs) requires specific calculation methods and input data. The aims of this study were to (i) identify existing NCD burden of disease (BoD) activities in Europe; (ii) collate information on data sources for mortality and morbidity; and (iii) provide an overview of NCD-specific methods for calculating NCD DALYs. Methods: NCD BoD studies were systematically searched in international electronic literature databases and in grey literature. We included all BoD studies that used the DALY metric to quantify the health impact of one or more NCDs in countries belonging to the European Region. Results: A total of 163 BoD studies were retained: 96 (59%) were single-country or sub-national studies and 67 (41%) considered more than one country. Of the single-country studies, 29 (30%) consisted of secondary analyses using existing Global Burden of Disease (GBD) results. Mortality data were mainly derived (49%) from vital statistics. Morbidity data were frequently (40%) drawn from routine administrative and survey datasets, including disease registries and hospital discharge databases. The majority (60%) of national BoD studies reported mortality corrections. Multimorbidity adjustments were performed in 18% of national BoD studies. Conclusion: The number of national NCD BoD assessments across Europe increased over time, driven by an increase in BoD studies that consisted of secondary data analysis of GBD study findings. Ambiguity in reporting the use of NCD-specific BoD methods underlines the need for reporting guidelines of BoD studies to enhance the transparency of NCD BoD estimates across Europe.
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Department of Public Health, Erasmus Mc, University Medical Center, Rotterdam, 3000 CA, Netherlands
Department of Public Health and Primary Care, Ghent University, Ghent, Belgium
Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium
Department for Exposure Assessment and Environmental Health Indicators, German Environment Agency, Berlin, Germany
National Food Institute, Technical University of Denmark, Lyngby, Denmark
Department of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany
Al-Farabi Kazakh National University, Almaty, Kazakhstan
National Institute for Health Development, Tallinn, Estonia
Department of Health Economics and Social Security, Jagiellonian University Medical College, Krakow, Poland
Environmental Health and Nutrition Laboratory, Faculty of Medicine, University of Lisbon, Lisbon, Portugal
School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Carlos Iii Institute of Health, National School of Public Health, Madrid, Spain
Research Group on Nutrition: Molecular, Pathophysiological and Social Issues, Biomedical Research and Innovation Institute of Cádiz (INiBICA), University of Cádiz, Cádiz, Spain
Medicine School, University of Applied and Environmental Sciences, Bogota, Colombia
Department of Translational Physiology, Infectiology and Public Health, Ghent University, Merelbeke, Belgium
Department of Public Health
Department of Public Health and Primary Care
Department of Epidemiology and Public Health
Department for Exposure Assessment and Environmental Health Indicators
National Food Institute
Department of Epidemiology and Health Monitoring
Al-Farabi Kazakh National University
National Institute for Health Development
Department of Health Economics and Social Security
Environmental Health and Nutrition Laboratory
School of Public Health and Community Medicine
Carlos Iii Institute of Health
Research Group on Nutrition: Molecular
Medicine School
Department of Translational Physiology
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