Spotted Fever Group Rickettsioses among Hospitalized Patients and Circulation of Rickettsia in Ticks, Kazakhstan, 2019


Bumburidi Y.V. Berezovskiy D.V. Zhakipbayeva B.T. Horth R.Z. Millman A.J. Nicholson W.L. Zemtsova G.E. Seffren V. Maltseva E.R. Berdygulova Z.A. Ostapchuk Y.O. Perfilyeva Y.V. Dmitrovskiy A.M. Dukayeva Z.K. Shapiyeva Z.Z.H.
October 2025Centers for Disease Control and Prevention (CDC)

Emerging Infectious Diseases
2025#31Issue 101961 - 1968 pp.

Testing for spotted fever group rickettsioses (SFGR) signs (eschar or rash) were found in 87% of SFGR and the criteria for identifying suspected patients are patients; 79% had a rash, 48% had an eschar, and not routinely used in Kazakhstan. In 2019, we per- 13% had neither. Testing of suspected rickettsia casformed a cross-sectional study in 6 sentinel hospitals es resulted in a 27% increase in laboratory-detected in the Pavlodar region. We tested 105 hospitalized pa- SFGR over the mean of the previous 3 years (62 vs. tients with SFGR-like symptoms by using PCR or indi- 49). Broadening the case definition by including fever, rect immunofluorescence antibody assay and identified headache, or myalgia and expanding routine testing for 62 cases of SFGR. Most (78%) cases of disease were suspected cases of SFGR could contribute to improved caused by Rickettsia sibirica and R. raoultii. Cutaneous case detection and earlier treatment.



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US Centers for Disease Control and Prevention, Central Asia Office, Almaty, Kazakhstan
Centers for Disease Control and Prevention, Atlanta, GA, United States
Almaty Branch of the National Center for Biotechnology, Almaty, Kazakhstan
Pavlodar Regional Hospital named after Sultanov, Pavlodar, Kazakhstan
Scientific-Practical Center for Sanitary-Epidemiological Expertise and Monitoring, National Center for Public Healthcare, Ministry of Health, Almaty, Kazakhstan

US Centers for Disease Control and Prevention
Centers for Disease Control and Prevention
Almaty Branch of the National Center for Biotechnology
Pavlodar Regional Hospital named after Sultanov
Scientific-Practical Center for Sanitary-Epidemiological Expertise and Monitoring

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