Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence–Assisted ARIA Care Pathways (ARIA 2024)

Bousquet J. Schünemann H.J. Sousa-Pinto B. Zuberbier T. Togias A. Samolinski B. Bedbrook A. Czarlewski W. Hofmann-Apitius M. Litynska J. Vieira R.J. Anto J.M. Fonseca J.A. Brozek J. Bognanni A. Brussino L. Canonica G.W. Cherrez-Ojeda I. Cruz A.A. Vecillas L.D.L. Dykewicz M. Gemicioglu B. Giovannini M. Haahtela T. Jacobs M. Jacomelli C. Klimek L. Kvedariene V. Larenas-Linnemann D.E. Louis G. Lourenço O. Leemann L. Morais-Almeida M. Neves A.L. Nadeau K.C. Nowak A. Palamarchuk Y. Palkonen S. Papadopoulos N.G. Parmelli E. Pereira A.M. Pfaar O. Regateiro F.S. Savouré M. Taborda-Barata L. Toppila-Salmi S.K. Torres M.J. Valiulis A. Ventura M.T. Williams S. Yepes-Nuñez J.J. Yorgancioglu A. Zhang L. Zuberbier J. Abdul Latiff A.H. Abdullah B. Agache I. Al-Ahmad M. Al-Nesf M.A. Al Shaikh N.A. Amaral R. Ansotegui I.J. Asllani J. Balotro-Torres M.C. Bergmann K.-C. Bernstein J.A. Bindslev-Jensen C. Blaiss M.S. Bonaglia C. Bonini M. Bossé I. Braido F. Caballero-Fonseca F. Camargos P. Carreiro-Martins P. Casale T. Castillo-Vizuete J.-A. Cecchi L. Teixeira M.D.C. Chang Y.-S. Loureiro C.C. Christoff G. Ciprandi G. Cirule I. Correia-de-Sousa J. Costa E.M. Cvetkovski B. de Vries G. Del Giacco S. Devillier P. Dokic D. Douagui H. Durham S.R. Enecilla M.L. Fiocchi A. Fokkens W.J. Fontaine J.-F. Gawlik R. Gereda J.E. Gil-Mata S. Giuliano A.F.M. Gotua M. Gradauskiene B. Guzman M.A. Hossny E. Hrubiško M. Iinuma T. Irani C. Ispayeva Z. Ivancevich J.C. Jartti T. Jeseňák M. Julge K. Jutel M. Kaidashev I. Bennoor K.S. Khaltaev N. Kirenga B. Kraxner H. Kull I. Kulus M. Kuna P. Kupczyk M. Kurchenko A. La Grutta S. Lane S. Miculinic N. Lee S.M. Le Thi Tuyet L. Lkhagvaa B. Louis R. Mahboub B. Makela M. Makris M. Maurer M. Melén E. Milenkovic B. Mohammad Y. Moniuszko M. Montefort S. Moreira A. Moreno P. Mullol J. Nadif R. Nakonechna A. Navarro-Locsin C.G. Neffen H.E. Nekam K. Niedoszytko M. Nunes E. Nyembue D. OHehir R. Ollert M. Ohta K. Okamoto Y. Okubo K. Olze H. Padukudru M.A. Palomares O. Pali-Schöll I. Panzner P. Palosuo K. Park H.S. Passalacqua G. Patella V. Pawankar R. Pétré B. Pitsios C. Plavec D. Popov T.A. Puggioni F. Quirce S. Raciborski F. Ramonaité A. Recto M. Repka-Ramirez S. Roberts G. Robles-Velasco K. Roche N. Rodriguez-Gonzalez M. Romualdez J.A. Rottem M. Rouadi P.W. Salapatas M. Sastre J. Serpa F.S. Sayah Z. Scichilone N. Senna G. Sisul J.C. Solé D. Soto-Martinez M.E. Sova M. Sozinova O. Stevanovic K. Ulrik C.S. Szylling A. Tan F.M. Tantilipikorn P. Todo-Bom A. Tomic-Spiric V. Tsaryk V. Tsiligianni I. Urrutia-Pereira M. Rostan M.V. Sofiev M. Valovirta E. Van Eerd M. Van Ganse E. Vasankari T. Vichyanond P. Viegi G. Wallace D. Wang D.Y. Waserman S. Wong G. Worm M. Yusuf O.M. Zaitoun F. Zidarn M.
October 2024 American Academy of Allergy, Asthma and Immunology

Journal of Allergy and Clinical Immunology: In Practice
2024 #12 Issue 10 2648 - 2668.e2 pp.

The traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients’ resources and abilities to be experts in their own lives based on their lived experiences. Improving healthcare safety, quality, and coordination, as well as quality of life, is an important aim in the care of patients with chronic conditions. Person-centered care needs to ensure that peoples values and preferences guide clinical decisions. This paper reviews current knowledge to develop (1) digital care pathways for rhinitis and asthma multimorbidity and (2) digitally enabled, person-centered care.¹ It combines all relevant research evidence, including the so-called real-world evidence, with the ultimate goal to develop digitally enabled, patient-centered care. The paper includes (1) Allergic Rhinitis and its Impact on Asthma (ARIA), a 2-decade journey, (2) Grading of Recommendations, Assessment, Development and Evaluation (GRADE), the evidence-based model of guidelines in airway diseases, (3) mHealth impact on airway diseases, (4) From guidelines to digital care pathways, (5) Embedding Planetary Health, (6) Novel classification of rhinitis and asthma, (7) Embedding real-life data with population-based studies, (8) The ARIA-EAACI (European Academy of Allergy and Clinical Immunology) strategy for the management of airway diseases using digital biomarkers, (9) Artificial intelligence, (10) The development of digitally enabled, ARIA person-centered care, and (11) The political agenda. The ultimate goal is to propose ARIA 2024 guidelines centered around the patient to make them more applicable and sustainable.

ARIA , Artificial intelligence , Asthma , Evidence-based medicine , mHealth , Person-centered care , Rhinitis

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Institute of Allergology, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany
ARIA, Montpellier, France
Department of Health Research Methods, Evidence, and Impact & Department of Medicine, McMaster University, Hamilton, ON, Canada
Department of Biomedical Science, Humanitas University, Pieve Emanuele, Milan, Italy
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal
CINTESIS@RISE—Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal
Division of Allergy, Immunology, and Transplantation (DAIT), National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Md, United States
Department of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland
Medical Consulting Czarlewski, Levallois, France
Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Bonn, Germany
Evidence Prime, Kracow, Poland
Gynecological and Obstetrician Polyclinic, District Hospital, Białystok, Poland
ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain
Department of Experimental Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain
Department of Epidemiology & Public Health, CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain
Department of Health Research Methods, Evidence, and Impact & Department of Medicine, Evidence in Allergy group, McMaster University, Hamilton, ON, Canada
Department of Medical Sciences, University of Torino, Torino, Italy
Allergy and Clinical Immunology Unit, Mauriziano Hospital, Torino, Italy
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy
Asthma & Allergy Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
Research Center Respiralab, Universidad Espíritu Santo, Samborondón, Ecuador
Department of Allergology & Pulmonology, Respiralab Research Group, Guayas, Guayaquil, Ecuador
Fundaçao ProAR, Federal University of Bahia and GARD/WHO Planning Group, Bahia, Salvador, Brazil
Department of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain
Section of Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, Mo, United States
Department of Pulmonary Diseases, Institute of Pulmonology & Tuberculosis, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey
Department of Health Sciences, University of Florence, Florence, Italy
Allergy Unit, Meyer Childrens Hospital IRCCS, Florence, Italy
Skin and Allergy Hospital, Helsinki University Hospital, University of Helsinki, Helsinki, Finland
“Respiriamo Insieme” Association, Asthma & Allergy Center, Padova, Italy
Department of Otolaryngology, Head & Neck Surgery, Universitätsmedizin Mainz, Mainz, Germany
Center for Rhinology and Allergology, Allergology & Rhinology Department, Wiesbaden, Germany
Institute of Clinical Medicine, Clinic of Chest Diseases and Allergology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
Institute of Biomedical Sciences, Department of Pathology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
Center of Excellence in Asthma and Allergy, Médica Sur Clinical Foundation and Hospital, México City, Mexico
Department of Public Health, University of Liège, Liège, Belgium
Faculty of Health Sciences and CICS—UBI, Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal
Department of Political Science, University of Zürich, Zürich, Switzerland
Allergy Center, CUF Descobertas Hospital, Lisbon, Portugal
Global Digital Health Unit, Department of Primary Care and Public Health, Imperial College, London, United Kingdom
Department of Environmental Health, Harvard TH Chan School of Public Health and Department of Medicine, Division of Allergy and Inflammation, Beth Israel Deaconess Hospital, Boston, Mass, United States
Finnish Meteorological Institute (FMI), Atmospheric Composition Research, Helsinki, Finland
EFA European Federation of Allergy and Airways Diseases Patients’ Associations, Brussels, Belgium
Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
PaCeIT—Patient Centered Innovation and Technologies, Center for Health Technology and Services Research (CINTESIS), Faculty of Medicine, University of Porto, Porto, Portugal
Allergy Unit, Instituto and Hospital CUF, Porto, Portugal
Section of Rhinology and Allergy, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Marburg, Philipps-Universität Marburg, Marburg, Germany
Allergy and Clinical Immunology Unit, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
Center for Innovative Biomedicine and Biotechnology (CIBB), Faculty of Medicine, University of Coimbra, Coimbra, Portugal
Institute of Immunology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
Université de Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)—UMR_S 1085, Rennes, France
Department of Immunoallergology, Cova da Beira University Hospital Centre, Covilhã, Portugal
UBIAir—Clinical & Experimental Lung Centre and CICS-UBI Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal
Department of Allergy, Skin and Allergy Hospital, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
Department of Otorhinolaryngology, University of Eastern Finland and the North Savo Wellbeing Services County, Kuopio, Finland
Allergy Unit, Málaga Regional University Hospital of Málaga, Malaga University, ARADyAL, Malaga, Spain
Clinic of Childrens Diseases, Institute of Clinical Medicine, Medical Faculty of Vilnius University, Vilnius, Lithuania
Clinic of Asthma, Allergy, and Chronic Lung Diseases, Asthma & Allergy Department, Vilnius, Lithuania
Allergy and Clinical Immunology, University of Bari Medical School, Bari, Italy
Institute of Sciences of Food Production, National Research Council (ISPA-CNR), Bari, Italy
International Primary Care Respiratory Group IPCRG, Edinburgh, United Kingdom
School of Medicine, Universidad de los Andes, DC, Bogotá, Colombia
Pulmonology Service, Internal Medicine Section, Fundación Santa Fe de Bogotá, University Hospital, DC, Bogotá, Colombia
Department of Pulmonary Diseases, Celal Bayar University, Faculty of Medicine, Manisa, Turkey
Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital and Beijing Institute of Otolaryngology, Beijing, China
Department of Otorhinolaryngology, Charité—Universitätsmedizin Berlin, Berlin, Germany
Allergy & Immunology Centre, Pantai Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
Department of Otorhinolaryngology—Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Kubang Kerian, Malaysia
Faculty of Medicine, Transylvania University, Brasov, Romania
Microbiology Department, College of Medicine, Kuwait University, Kuwait City, Kuwait
Adult Allergy and Immunology Division—Hamad Medical Corporation, Doha, Qatar
Otolaryngology Head & Neck Surgery Department, Mouwasat Hospital, Dammam, Saudi Arabia
Department of Cardiovascular and Respiratory Sciences, Porto Health School, Polytechnic Institute of Porto, Porto, Portugal
Department of Womens and Childrens Health, Paediatric Research, Uppsala University, Uppsala, Sweden
Department of Allergy and Immunology, Hospital Quironsalud Bizkaia, Bilbao, Spain
Department of Internal Medicine, University of Medicine, Tirana, Albania
Section of Allergy, Asthma and Immunology, University of Santo Tomas Hospital, Manila, Philippines
Division of Immunology, Allergy and Rheumatology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States
Department of Dermatology and Allergy Center, Odense Research Centre for Anaphylaxis (ORCA), Odense University Hospital, Odense, Denmark
Department of Pediatrics, Medical College of Georgia at Augusta University, Augusta, Ga, United States
Institute “Bona Sforza”, University for Linguistic Mediators, Bari, Italy
Department of Cardiovascular and Respiratory Sciences, Universita Cattolica del Sacro Cuore, Rome, Italy
Department of Neurological, ENT and Thoracic Sciences, Fondazione Policlinico Universitario A Gemelli—IRCCS, Rome, Italy
National Heart and Lung Institute (NHLI), Imperial College London, London, United Kingdom
Allergist, Department of Allergy, La Rochelle, France
Respiratory Clinic, Department of Internal Medicine, University of Genoa, Genoa, Italy
Respiratory & Allergy Clinic, IRCCS Ospedale Policlinico San Martino, Genoa, Italy
Centro Medico Docente La Trinidad, Allergology & Immunolgy Department, Caracas, Venezuela
Department of Pediatrics, Medical School, Federal University of Minas Gerais, Belo Horizonte, Brazil
NOVA Medical School/Comprehensive Health Research Centre (CHRC), Lisbon, Portugal
Serviço de Imunoalergologia, Centro Hospitalar Universitário de Lisboa Central/ULS São José, Lisbon, Portugal
Division of Allergy/Immunology, University of South Florida, Tampa, Fla, United States
Department of Respiratory Medicine, Hospital Universitari Dexeus, Barcelona, Spain
The Group of Rhinitis, Rhinosinusitis and Nasal Polyps, Area of Asthma, SEPAR, Barcelona, Spain
SOS Allergology and Clinical Immunology, USL Toscana Centro, Prato, Italy
Dr Agostinho Neto University hospital, Epidemiology Department, Praia, Cape Verde
Immunology, Cabo Verde University, Faculty of Medicine, Praia, Cape Verde
Division of Allergy and Clinical Immunology, Seoul National University Bundang Hospital, Seoul National University, College of Medicine, Seoul, South Korea
Department of Pneumology, Coimbra University Hospital, Faculty of Medicine, Coimbra, Portugal
Coimbra Institute for Clinical and Biomedical Research, CIBB, Coimbra, Portugal
Faculty of Public Health, Sofia Medical University, Sofia, Bulgaria
Casa di Cura Villa Montallegro, Allergology Department, Genova, Italy
Latvian Association of Allergists, University Children Hospital, Riga, Latvia
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
CINTESIS@RISE, Biochemistry Lab, Faculty of Pharmacy and Competence Center on Active and Healthy Ageing, University of Porto, Porto, Portugal
Woolcock Institute of Medical Research, Quality Use of Respiratory Medicine, Sydney, NSW, Australia
Peercode BV, Geldermalsen, Netherlands
Department of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology, University Hospital “Duilio Casula”, University of Cagliari, Cagliari, Italy
VIM Suresnes, UMR 0892, Pôle des Maladies des Voies Respiratoires, Hôpital Foch, Université Paris-Saclay, Suresnes, France
Medical Faculty Skopje, University Clinic of Pulmology and Allergy, Skopje, North Macedonia
Service de Pneumo-Allergologie, Centre Hospitalo-Universitaire de Béni-Messous, Algiers, Algeria
Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, London, United Kingdom
St Lukes Medical Center, ENT Department, Quezon City, Philippines
Allergy, Bambino Gesù Childrens Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy
Department of Otorhinolaryngology, Amsterdam University Medical Centres, AMC, Amsterdam, Netherlands
CHU de Reims, Service des Maladies Respiratoires et Allergiques, Reims, France
Department of Internal Diseases, Allergology and Clinical Immunology, Medical University of Silesia in Katowice, Katowice, Poland
Clínica Ricardo Palma, Allergy & Immunology Department, Lima, Peru
Department of Internal Medicine ‘A. Murri’ and Unit of Geriatric Immunoallergology, University of Bari Medical School, Bari, Italy
Center of Allergy and Immunology, David Tvildiani Medical University, Tbilisi, Georgia
Department of Immunology and Allergology, Lithuanian University of Health Sciences, Kaunas, Lithuania
Immunology and Allergy Division, Clinical Hospital, University of Chile, Santiago, Chile
Pediatric Allergy, Immunology and Rheumatology Unit, Childrens Hospital, Ain Shams University, Cairo, Egypt
Department of Clinical Immunology and Allergy, Oncology Institute of St Elisabeth, Bratislava, Slovakia
Department of Otorhinolaryngology, Chiba University, Chiba, Japan
Department of Internal Medicine and Infectious Diseases, St Joseph University, Hotel Dieu de France Hospital, Beirut, Lebanon
Department of Allergology and Clinical Immunology, Kazakhstan Association of Allergology and Clinical Immunology, Kazakh National Medical University, Almaty, Kazakhstan
Servicio de Alergia e Immunologia, Clinica Santa Isabel, Buenos Aires, Argentina
Research Unit of Clinical Medicine, University of Oulu, Oulu, Finland
Department of Pediatrics and Adolescent Medicine, University of Turku, Turku University Hospital, Turku, Finland
Department of Pulmonology and Phthisiology, Department of Pediatrics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Bratislava, Slovakia
Institute of Clinical Immunology and Allergology, Jessenius Faculty of Medicine in Martin, Comenius University, Bratislava, Slovakia
Institute of Clinical Medicine, Childrens Clinic, Tartu University, Tartu, Estonia
Department of Clinical Immunology, Wrocław Medical University, Wroclaw, Poland
ALL-MED Medical Research Institute, Department of Clinical Immunology, Wroclaw, Poland
Poltava State Medical University, Immunology & Allergology Department, Poltava, Ukraine
Department of Respiratory Medicine, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh
Global NCD Platform, Geneva, Switzerland
Makerere University Lung Institute, Pulmonology Medicine Department, Kampala, Uganda
Department of Otorhinolaryngology, Head and Neck Surgery, Semmelweis University, Budapest, Hungary
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden
Sachs Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden
Department of Pediatric Respiratory Diseases and Allergology, Medical University of Warsaw, Warsaw, Poland
Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland
Department of Clinical and Laboratory Immunology, Allergology and Medical Genetics, Bogomolets National Medical University, Kyiv, Ukraine
Institute of Translational Pharmacology (IFT)-National Research Council (CNR), Palermo, Italy
Respiratory Medicine, Trinity College, Dublin, Ireland
Respiratory Physician & Allergist, Professorial Respiratory Centre, Tallaght University Hospital & Peamount Healthcare, Dublin, Ireland
Croatian Pulmonary Society, Clinical Center for Pulmonary Diseases, Zagreb, Croatia
Dankook University Hospital, ENT Department, Cheonan, South Korea
Asthma, COPD Outpatient Care Unit, University Medical Center, Hô-Chi-Minh City, Viet Nam
Mongolian National University of Medical Sciences, Health Department, Ulan Bator, Mongolia
Department of Pulmonary Medicine, CHU Liège, Liège, Belgium
GIGA I3 Research Group, University of Liège, Liège, Belgium
Rashid Hospital, DUBAI Health, Dubai, United Arab Emirates
Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates
Allergy Unit “D Kalogeromitros”, 2nd Department of Dermatology and Venereology, National & Kapodistrian University of Athens, “Attikon” University Hospital, Athens, Greece
Clinic for Pulmonary Diseases, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Serbian Association for Asthma and COPD, Belgrade, Serbia
National Center for Research in Chronic Respiratory Diseases, Collaborating with WHO—EMRO Tishreen University School of Medicine, Latakia, Syrian Arab Republic
Al-Sham Private University, Pharmacy Department, Damascus, Syrian Arab Republic
Department of Allergology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
Department of Medicine, Faculty of Medicine and Surgery, University of Malta, MSD, Msida, Malta
EPIUnit-Institute of Public Health, University of Porto, Laboratory for Integrative and Translational Research in Population Health (ITR), Porto, Portugal
Serviço de Imunoalergologia, Centro Hospitalar Universitário São João, Porto, Portugal
Basic and Clinical Immunology Unit, Department of Pathology, Faculty of Medicine, University of Porto, Porto, Portugal
Fundaler, Buenos Aires, Argentina
Rhinology Unit & Smell Clinic, ENT Department, Hospital Clínic, Barcelona, Spain
Clinical & Experimental Respiratory Immunoallergy, FRCB-IDIBAPS, CIBERES, University of Barcelona, Barcelona, Spain
Université Paris-Saclay, UVSQ, Univ. Paris-Sud, Villejuif, France
Inserm, Équipe dÉpidémiologie respiratoire intégrative, CESP, Villejuif, France
Clinical Immunology and Allergy Unit, Sheffield Teaching Hospitals, Sheffield, United Kingdom
University of Liverpool, Liverpool, United Kingdom
Department of Otolaryngology-Head & Neck Surgery, St Lukes Medical Center, Quezon City, Philippines
Division of Surgery, Philippine Childrens Medical Center, Quezon City, Philippines
Center of Allergy, Immunology and Respiratory Diseases, Santa Fe, Argentina
Hungarian Allergy Association, Allergy & Immunology Department, Budapest, Hungary
Department of Allergology, Medical University of Gdańsk, Gdansk, Poland
Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique
ENT Department, University Hospital of Kinshasa, Kinshasa, Congo
Allergy, Asthma and Clinical Immunology, Alfred Health and Department of Immunology, Central Clinical School, Monash University, Melbourne, VIC, Australia
Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg
Department of Dermatology and Allergy Center, Odense Research Center for Anaphylaxis (ORCA), Odense University Hospital, Odense, Denmark
Japan Antituberculosis Association (JATA), Fukujuji Hospital, Tokyo, Japan
Chiba Rosai Hospital, ENT Department, Chiba, Japan
Chiba University Hospital, Department of Otolaryngology, Head and Neck Surgery, Chiba, Japan
Deparment of Otolaryngology, Nippon Medical School, Tokyo, Japan
Department of Respiratory Medicine, JSS Medical College, JSSAHER Mysuru, Karnataka, India
Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Madrid, Spain
Institute of Pathophysiology and Allergy Research, Medical University Vienna, Vienna, Austria
Interuniversity Messerli Research Institute of the University of Veterinary Medicine and Medical University Vienna, Vienna, Austria
Department of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
Department of Allergology, University of Helsinki and Hospital for Skin and Allergic Diseases, Helsinki, Finland
Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea
Allergy and Respiratory Diseases, IRCCS Policlinico San Martino, University of Genoa, Genoa, Italy
Division of Allergy and Clinical Immunology, Department of Medicine, “Santa Maria della Speranza” Hospital, Battipaglia, Salerno, Italy
Agency of Health ASL, Division of Allergy and Clinical Immunology, Department of Medicine, Salerno, Italy
Postgraduate Programme in Allergy and Clinical Immunology, University of Naples Federico II, Naples, Italy
Department of Pediatrics, Nippon Medical School, Tokyo, Japan
Medical School, University of Cyprus, Nicosia, Cyprus
Prima Nova, Healthcare Institution, Zagreb, Croatia
Medical Faculty, University JJ Strossmayer of Osijek, Osijek, Croatia
Clinic of Occupational Diseases, University Hospital Sveti Ivan Rilski, Sofia, Bulgaria
IRCCS Humanitas Research Center, Personalized Medicine Asthma & Allergy, Rozzano, Milan, Italy
Department of Pulmonology and Allergology, Klaipeda National Hospital, Klaipeda, Lithuania
Vilnius University Medical Faculty, Department of Political Behaviour and Institutions, Vilnius, Lithuania
Division of Adult and Pediatric Allergy and Immunology, University of the Philippines - Philippines General Hospital, Manila, Philippines
Department of Allergy, Clinics Hospital, National University, San Lorenzo, Paraguay
Faculty of Medicine, University of Southampton, Southampton, United Kingdom
The David Hide Asthma and Allergy Centre, St Marys Hospital, Isle of Wight, United Kingdom
NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom
Pneumologie, AP-HP Centre Université de Paris Cité, Hôpital Cochin, Paris, France
UMR 1016, Institut Cochin, Paris, France
Inserm, Epidemiology Department, CESP, Villejuif, France
Pediatric Allergy and Clinical Immunology, Hospital Espanol de Mexico, Mexico City, Mexico
Faculty of Medicine & Surgery, University of Santo Tomas, Manila, Philippines
Division of Allergy, Asthma and Clinical Immunology, Emek Medical Center, Afula, Israel
Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
Department of Otolaryngology-Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon
Department of Otorhinolaryngology-Head and Neck Surgery, Dar Al Shifa Hospital, Salmiya, Kuwait
ARIA, Asthma, Rhinitis, Immunology & Allergy Department, Athens, Greece
Allergy Service, Fundacion Jimenez Diaz, Autonoma University of Madrid, CIBERES-ISCIII, Madrid, Spain
Asthma Reference Center—School of Medicine of Santa Casa de Misericórdia of Vitória, Espírito Santo, Brazil
SMAIC Société Marocaine dAllergologie et Immunologie Clinique, Rabat, Morocco
PROMISE Department, University of Palermo, Palermo, Italy
Asthma-Allergy Unit, University Hospital of Verona, Verona, Italy
Clínica Sisul, Allergy & Asthma, Medical Director, CLINICA SISUL, FACAAI, SPAAI, Asuncion, Paraguay
Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil
Division of Respiratory Medicine, Department of Pediatrics, Hospital Nacional de Niños, Universidad de Costa Rica, San Jose, Costa Rica
Department of Respiratory Medicine and Tuberculosis, University Hospital, Brno, Czech Republic
Head of Laboratory of Atmospheric processes and Aerobiology, University of Latvia, Riga, Latvia
Department of Respiratory Medicine, Copenhagen University Hospital-Hvidovre, Copenhagen, Denmark
Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Department of Pediatrics, Victor R Potenciano Medical Center, Mandaluyong, Philippines
Department of Otolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Imunoalergologia, Centro Hospitalar Universitário de Coimbra, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
Clinic of Allergology and Immunology, University Clinical Center of Serbia, Belgrade, Serbia
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
International Primary Care Respiratory Group IPCRG, Aberdeen, United Kingdom
Health Planning Unit, Department of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece
Federal University of Pampa, Department of Medicine, Uruguaiana, Brazil
Pediatrics, Allergy & Immunology, Latín American Society of Allergy, Asthma & immunology (SLAAi), Montevideo, Uruguay
Department of Lung Diseases and Clinical Immunology, University of Turku, Turku, Finland
Research on Healthcare Performance (RESHAPE), INSERM U1290, Pneumologie et Medicine Respiratoire, Groupement Hospitalier Nord, Hôpital de la Croix Rousse, Lyon, France
FiLHA, Finnish Lung Health Association, Helsinki, Finland
Department of Clinical Medicine, Pulmonary Diseases and Clinical Allergology, University of Turku, Turku, Finland
Division of Allergy and Immunology, Department of Pediatrics, Siriraj Hospital, Mahidol University Faculty of Medicine, Bangkok, Thailand
Pulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Pisa, Italy
Nova Southeastern University, College of Allopathic Medicine, Fort Lauderdale, Fla, United States
Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
Department of Medicine, Clinical Immunology and Allergy, McMaster University, Hamilton, ON, Canada
Department of Paediatrics, Prince of Wales Hospital, SAR, Hong Kong, Hong Kong
Division of Allergy and Immunology, Department of Dermatology, Allergy and Venerology, Charité Universitätsmedizin Berlin, Berlin, Germany
The Allergy and Asthma Institute, Allergy & Asthma Department, Islamabad, Pakistan
Clemenceau Medical Center DHCC, Lebanese-American University, Dubai, United Arab Emirates
University Clinic of Respiratory and Allergic Diseases, Pulmonary & Allergy Department, Golnik, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

Institute of Allergology
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
ARIA
Department of Health Research Methods
Department of Biomedical Science
MEDCIDS—Department of Community Medicine
CINTESIS@RISE—Health Research Network
Division of Allergy
Department of Prevention of Environmental Hazards
Medical Consulting Czarlewski
Department of Bioinformatics
Evidence Prime
Gynecological and Obstetrician Polyclinic
ISGlobal
Department of Experimental Sciences
Department of Epidemiology & Public Health
Department of Health Research Methods
Department of Medical Sciences
Allergy and Clinical Immunology Unit
Department of Biomedical Sciences
Asthma & Allergy Unit
Research Center Respiralab
Department of Allergology & Pulmonology
Fundaçao ProAR
Department of Allergy
Section of Allergy and Immunology
Department of Pulmonary Diseases
Department of Health Sciences
Allergy Unit
Skin and Allergy Hospital
“Respiriamo Insieme” Association
Department of Otolaryngology
Center for Rhinology and Allergology
Institute of Clinical Medicine
Institute of Biomedical Sciences
Center of Excellence in Asthma and Allergy
Department of Public Health
Faculty of Health Sciences and CICS—UBI
Department of Political Science
Allergy Center
Global Digital Health Unit
Department of Environmental Health
Finnish Meteorological Institute (FMI)
EFA European Federation of Allergy and Airways Diseases Patients’ Associations
Allergy Department
PaCeIT—Patient Centered Innovation and Technologies
Allergy Unit
Section of Rhinology and Allergy
Allergy and Clinical Immunology Unit
Center for Innovative Biomedicine and Biotechnology (CIBB)
Institute of Immunology
Université de Rennes
Department of Immunoallergology
UBIAir—Clinical & Experimental Lung Centre and CICS-UBI Health Sciences Research Centre
Department of Allergy
Department of Otorhinolaryngology
Allergy Unit
Clinic of Childrens Diseases
Clinic of Asthma
Allergy and Clinical Immunology
Institute of Sciences of Food Production
International Primary Care Respiratory Group IPCRG
School of Medicine
Pulmonology Service
Department of Pulmonary Diseases
Department of Otolaryngology
Department of Otorhinolaryngology
Allergy & Immunology Centre
Department of Otorhinolaryngology—Head and Neck Surgery
Faculty of Medicine
Microbiology Department
Adult Allergy and Immunology Division—Hamad Medical Corporation
Otolaryngology Head & Neck Surgery Department
Department of Cardiovascular and Respiratory Sciences
Department of Womens and Childrens Health
Department of Allergy and Immunology
Department of Internal Medicine
Section of Allergy
Division of Immunology
Department of Dermatology and Allergy Center
Department of Pediatrics
Institute “Bona Sforza”
Department of Cardiovascular and Respiratory Sciences
Department of Neurological
National Heart and Lung Institute (NHLI)
Allergist
Respiratory Clinic
Respiratory & Allergy Clinic
Centro Medico Docente La Trinidad
Department of Pediatrics
NOVA Medical School/Comprehensive Health Research Centre (CHRC)
Serviço de Imunoalergologia
Division of Allergy/Immunology
Department of Respiratory Medicine
The Group of Rhinitis
SOS Allergology and Clinical Immunology
Dr Agostinho Neto University hospital
Immunology
Division of Allergy and Clinical Immunology
Department of Pneumology
Coimbra Institute for Clinical and Biomedical Research
Faculty of Public Health
Casa di Cura Villa Montallegro
Latvian Association of Allergists
Life and Health Sciences Research Institute (ICVS)
CINTESIS@RISE
Woolcock Institute of Medical Research
Peercode BV
Department of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology
VIM Suresnes
Medical Faculty Skopje
Service de Pneumo-Allergologie
Allergy and Clinical Immunology
St Lukes Medical Center
Allergy
Department of Otorhinolaryngology
CHU de Reims
Department of Internal Diseases
Clínica Ricardo Palma
Department of Internal Medicine ‘A. Murri’ and Unit of Geriatric Immunoallergology
Center of Allergy and Immunology
Department of Immunology and Allergology
Immunology and Allergy Division
Pediatric Allergy
Department of Clinical Immunology and Allergy
Department of Otorhinolaryngology
Department of Internal Medicine and Infectious Diseases
Department of Allergology and Clinical Immunology
Servicio de Alergia e Immunologia
Research Unit of Clinical Medicine
Department of Pediatrics and Adolescent Medicine
Department of Pulmonology and Phthisiology
Institute of Clinical Immunology and Allergology
Institute of Clinical Medicine
Department of Clinical Immunology
ALL-MED Medical Research Institute
Poltava State Medical University
Department of Respiratory Medicine
Global NCD Platform
Makerere University Lung Institute
Department of Otorhinolaryngology
Department of Clinical Science and Education
Sachs Children and Youth Hospital
Department of Pediatric Respiratory Diseases and Allergology
Division of Internal Medicine
Department of Clinical and Laboratory Immunology
Institute of Translational Pharmacology (IFT)-National Research Council (CNR)
Respiratory Medicine
Respiratory Physician & Allergist
Croatian Pulmonary Society
Dankook University Hospital
Asthma
Mongolian National University of Medical Sciences
Department of Pulmonary Medicine
GIGA I3 Research Group
Rashid Hospital
Research Institute of Medical and Health Sciences
Allergy Unit “D Kalogeromitros”
Clinic for Pulmonary Diseases
National Center for Research in Chronic Respiratory Diseases
Al-Sham Private University
Department of Allergology and Internal Medicine
Department of Medicine
EPIUnit-Institute of Public Health
Serviço de Imunoalergologia
Basic and Clinical Immunology Unit
Fundaler
Rhinology Unit & Smell Clinic
Clinical & Experimental Respiratory Immunoallergy
Université Paris-Saclay
Inserm
Clinical Immunology and Allergy Unit
University of Liverpool
Department of Otolaryngology-Head & Neck Surgery
Division of Surgery
Center of Allergy
Hungarian Allergy Association
Department of Allergology
Faculty of Medicine
ENT Department
Allergy
Department of Infection and Immunity
Department of Dermatology and Allergy Center
Japan Antituberculosis Association (JATA)
Chiba Rosai Hospital
Chiba University Hospital
Deparment of Otolaryngology
Department of Respiratory Medicine
Department of Biochemistry and Molecular Biology
Institute of Pathophysiology and Allergy Research
Interuniversity Messerli Research Institute of the University of Veterinary Medicine and Medical University Vienna
Department of Immunology and Allergology
Department of Allergology
Department of Allergy and Clinical Immunology
Allergy and Respiratory Diseases
Division of Allergy and Clinical Immunology
Agency of Health ASL
Postgraduate Programme in Allergy and Clinical Immunology
Department of Pediatrics
Medical School
Prima Nova
Medical Faculty
Clinic of Occupational Diseases
IRCCS Humanitas Research Center
Department of Pulmonology and Allergology
Vilnius University Medical Faculty
Division of Adult and Pediatric Allergy and Immunology
Department of Allergy
Faculty of Medicine
The David Hide Asthma and Allergy Centre
NIHR Southampton Biomedical Research Centre
Pneumologie
UMR 1016
Inserm
Pediatric Allergy and Clinical Immunology
Faculty of Medicine & Surgery
Division of Allergy
Rappaport Faculty of Medicine
Department of Otolaryngology-Head and Neck Surgery
Department of Otorhinolaryngology-Head and Neck Surgery
ARIA
Allergy Service
Asthma Reference Center—School of Medicine of Santa Casa de Misericórdia of Vitória
SMAIC Société Marocaine dAllergologie et Immunologie Clinique
PROMISE Department
Asthma-Allergy Unit
Clínica Sisul
Division of Allergy
Division of Respiratory Medicine
Department of Respiratory Medicine and Tuberculosis
Head of Laboratory of Atmospheric processes and Aerobiology
Department of Respiratory Medicine
Institute of Clinical Medicine
Department of Pediatrics
Department of Otolaryngology
Imunoalergologia
Clinic of Allergology and Immunology
Faculty of Medicine
International Primary Care Respiratory Group IPCRG
Health Planning Unit
Federal University of Pampa
Pediatrics
Department of Lung Diseases and Clinical Immunology
Research on Healthcare Performance (RESHAPE)
FiLHA
Department of Clinical Medicine
Division of Allergy and Immunology
Pulmonary Environmental Epidemiology Unit
Nova Southeastern University
Department of Otolaryngology
Department of Medicine
Department of Paediatrics
Division of Allergy and Immunology
The Allergy and Asthma Institute
Clemenceau Medical Center DHCC
University Clinic of Respiratory and Allergic Diseases
Faculty of Medicine

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