Medicinal Plants for Skin Disorders: Phytochemistry and Pharmacological Insights


Bolatkyzy N. Shepilov D. Turmanov R. Berillo D. Vassilina T. Ibragimova N. Berganayeva G. Dyusebaeva M.
August 2025Multidisciplinary Digital Publishing Institute (MDPI)

Molecules
2025#30Issue 15

Skin disorders are common and often chronic conditions with significant therapeutic challenges. Limitations of conventional treatments, such as adverse effects and antimicrobial resistance, have increased interest in plant-based alternatives. This article presents the phytochemical composition and pharmacological potential of several medicinal plants traditionally used in the treatment of skin diseases, including Rubus vulgaris, Plantago major, Artemisia terrae-albae, and Eryngium planum. Based on an analysis of scientific literature, the presence of bioactive compounds—including flavonoids, anthocyanins, phenolic acids, tannins, and sesquiterpenes—is summarized, along with their antioxidant, anti-inflammatory, and antimicrobial effects. Emphasis is placed on the correlation between traditional ethnomedicinal applications and pharmacological mechanisms. The findings support the potential of these species as sources for dermatological phytotherapeutics. Further research is needed to standardize active constituents, assess safety, and conduct clinical validation.

anthocyanins , anti-inflammatory effect , antioxidant activity , bioactive compounds , flavonoids , medicinal plants , phytochemistry , sesquiterpenes , skin diseases , traditional medicine

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Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, 71 Al-Farabi Avenue, Almaty, 050042, Kazakhstan
Department of Chemistry, Abai Kazakh National Pedagogical University, Dostyk Avenue 13, Almaty, 050010, Kazakhstan
Center of Agro Competence, M. Kozybayev North-Kazakhstan University, Petropavlovsk, 150000, Kazakhstan
Kazakh National Agrarian Research University, St. Named After Valikhanov 137, Almaty, 050000, Kazakhstan
Faculty of Engineering and Information Technologies, Kazakh-German University (DKU), Almaty, 050010/A26C7F8, Kazakhstan

Faculty of Chemistry and Chemical Technology
Department of Chemistry
Center of Agro Competence
Kazakh National Agrarian Research University
Faculty of Engineering and Information Technologies

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