Acromegaly: Clinical Care in Central and Eastern Europe, Israel, and Kazakhstan
Bolanowski M. Adnan Z. Doknic M. Guk M. Hána V. Ilovayskaya I. Kastelan D. Kocjan T. Kužma M. Nurbekova A. Poiana C. Szücs N. Vandeva S. Gomez R. Paidac S. Simoneau D. Shimon I.
22 February 2022Frontiers Media S.A.
Frontiers in Endocrinology
2022#13
Acromegaly is a rare condition typically caused by benign pituitary adenomas, resulting in excessive production of growth hormone. Clinical manifestations of acromegaly are diverse, varying from the overgrowth of body tissue to cardiovascular, metabolic, and osteoarticular disorders. Symptoms may emerge slowly, overlapping with other diseases and often involve many different healthcare specialists. In the last decade, efforts to provide an accurate and timely diagnosis of acromegaly have improved disease management and clinical experience. Despite this progress, marked differences in the diagnosis, treatment, and management of acromegaly exist from country-to-country. To address these inconsistencies in the region comprising Central and Eastern Europe, Israel, and Kazakhstan, a panel of acromegaly experts from 13 of these countries was convened. Acromegaly experts from each country provided available information on the approaches from their country, including regional treatment centers and multidisciplinary teams, treatment access, reimbursement and availability, and physician education, disease awareness, and patient advocacy. Across several areas of acromegaly management, divergent approaches were identified and discussed, including the provision of multidisciplinary care, approved and available treatments, and disease awareness programs. These were recognized as areas of potential improvement in the management of acromegaly, in addition to participation in national and regional acromegaly registries. Further experience exchange will facilitate the identification of specific strategies that can be adapted in each country, and widespread participation in acromegaly registries will enable their evaluation. It is anticipated that this approach will support the optimization of acromegaly patient care across this region. Copyright
acromegaly , endocrinology , IGF-I , multidisciplinary care , referral pathway
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Department of Endocrinology, Diabetes and Isotope Therapy, Wroclaw Medical University, Wroclaw, Poland
Division of Endocrinology and Metabolism, Bar Ilan Faculty of Medicine, Clalit Medical Health Care Services, Safed, Israel
Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Medical Faculty, University of Belgrade, Belgrade, Serbia
Department of Transsphenoidal Surgery, Romodanov Neurosurgery Institute, Kyiv, Ukraine
Third Department of Internal Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Neuroendocrine Unit, Endocrinology Department, Moscow Regional Research and Clinical Institute, Moscow, Russian Federation
Department of Endocrinology, University Hospital Center Zagreb, Zagreb, Croatia
Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
Comenius University, Faculty of Medicine, 5th Department of Internal Medicine, University Hospital Bratislava, Bratislava, Slovakia
Kazakh National Medical University, Almaty, Kazakhstan
Department of Endocrinology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Department of Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary
Department of Endocrinology, Specialized Hospital for Active Treatment of Endocrinology, Medical University, Sofia, Bulgaria
Global Medical Affairs, Pfizer Rare Disease, Brussels, Belgium
Medical Affairs, Pfizer Rare Disease, Bucharest, Romania
Central and Eastern Europe Medical Affairs, Pfizer Rare Disease, Paris, France
Rabin Medical Center, Petah-Tikva, Israel
Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Department of Endocrinology
Division of Endocrinology and Metabolism
Neuroendocrinology Department
Department of Transsphenoidal Surgery
Third Department of Internal Medicine
Neuroendocrine Unit
Department of Endocrinology
Department of Endocrinology
Faculty of Medicine
Comenius University
Kazakh National Medical University
Department of Endocrinology
Department of Internal Medicine and Oncology
Department of Endocrinology
Global Medical Affairs
Medical Affairs
Central and Eastern Europe Medical Affairs
Rabin Medical Center
Sackler Faculty of Medicine
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