Association Between Work Status and Quality of Life in End-Stage Renal Disease Patients During the First Year of Hemodialysis
Bodesova S.B. Sagandykova N.S. Danebek K. Sultanova B.G. Baurzhan M.B. Onalbekov Y.S.
July 2025John Wiley and Sons Inc
Hemodialysis International
2025#29Issue 3381 - 389 pp.
Introduction: End-stage renal disease patients have impaired health-related quality of life as compared to the general population due to the combined effects of the disease and hemodialysis (HD) therapy. As a result, poor quality of life increases their risk of mortality and hospitalization and affects their general well-being. While existing rehabilitation programs aim to improve physical activity in HD patients, the link between work status, particularly within the first year of treatment, and their quality of life remains unclear. Objectives: This study aimed to compare the quality of life of working and nonworking end-stage renal disease patients during their first year of HD. Materials and Methods: The comparative cross-sectional study involved 120 patients (60 working, 60 non- working) with end-stage renal disease at the hemodialysis (HD) centers during their first year of HD. Patients were administered the SF-36 survey to determine their physical and mental health levels. Statistical analyses, including Mann–Whitney U tests, Spearmans correlation, and multiple regression, were performed using SPSS 22. Results: Employed patients demonstrated significantly higher physical functioning (MR = 82.37, Me = 41.27) and mental health (MR = 74.33, Me = 47.22) scores compared to non-employed (MR = 38,63, Me = 29.07 and MR = 46.67, Me = 38,14, respectively) (p < 0.001). Employment is a significant predictor of high quality of life (B = 11.6 for PF, B = 6.5 for MH). Despite older age and increased prevalence of comorbidities, employed patients demonstrate better quality of life results. Conclusion: Employment has a positive effect on the quality of life of patients with chronic renal failure receiving HD, indicating that their regimen may be improved by incorporating work into the treatment program. Employment opportunities for patients with chronic renal failure receiving dialysis should be explored in the future.
end-stage renal disease , hemodialysis therapy , quality of life , rehabilitation programs , working patients
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Nephrology Department, Kazakh National University Named After S.D. Asfendiyarov, Almaty, Kazakhstan
Internal Medicine Department, University Medical Center, Astana, Kazakhstan
School of Medicine, Nazarbayev University, Astana, Kazakhstan
PF National Kidney Fund of the Republic of Kazakhstan, Almaty, Kazakhstan
Research Institute of Balneology and Medical Rehabilitation of the Ministry of Health of the Republic of Kazakhstan, Astana, Kazakhstan
Astana Medical University Kazakhstan, Astana, Kazakhstan
LLP “Scientific Center for Professional Training”, Astana, Kazakhstan
Nephrology Department
Internal Medicine Department
School of Medicine
PF National Kidney Fund of the Republic of Kazakhstan
Research Institute of Balneology and Medical Rehabilitation of the Ministry of Health of the Republic of Kazakhstan
Astana Medical University Kazakhstan
LLP “Scientific Center for Professional Training”
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