Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders


Bjørklund G. Shanaida M. Gontova T. Gheorghe E. Kassym L. Kussainova A. Voloshyn V. Semenova Y. Lysiuk R. Voloshyn O. Shanaida V. Hangan T.
2025Bentham Science Publishers

Current Medicinal Chemistry
2025#32Issue 357804 - 7830 pp.

Skin is the human bodys largest organ, protecting it from various environmental threats. At the same time, it is the most accessible organ of the body, which ensures the reception of stimuli and contact with the environment. Such common signs of skin aging, such as wrinkles, fine lines, and discoloration, result from both extrinsic and intrinsic factors that act for a long time. If the skin does not look well enough, it is worth investigating whether minerals or trace elements are deficient. The positive role of some minerals (calcium, potassium, sodium, sulfur, and magnesium) and trace elements (iron, zinc, selenium, copper, manganese, and silicon) was found in maintaining skin health. There are also a variety of skin conditions, such as inflammatory disorders (eczema, psoriasis), acne, lichen planus, vitiligo, alopecia areata, or even skin cancer, which require specific approaches for their prevention and treatment considering the saturation of the body and the skin with mineral elements. They could be supplied internally (through adequate nutrition or food additives) or externally (by application of cosmetics). Some aspects of the danger of the toxic trace elements used in cosmetics are also described in this review. Bentham Science Publishers

antioxidants , dermatology , lichen planus , nutritional deficiencies , Skin health , trace elements

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Council for Nutritional and Environmental Medicine (CONEM), Mo i Rana, Norway
I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
CONEM Ukraine Natural Drugs Research Group, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
National University of Pharmacy, Kharkiv, Ukraine
Faculty of Medicine, Ovidius University of Constanta, Constanta, Romania
Department of General Medical Practice with a Course of Evidence-Based Medicine, NJSC “Astana MedicalUniversity”, Astana, Kazakhstan
School of Medicine, Nazarbayev University, Astana, Kazakhstan
Department of Pharmacognosy and Botany, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine
CONEM Ukraine Life Science Research Group, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine
Ternopil Ivan Puluj National Technical University, Ternopil, Ukraine

Council for Nutritional and Environmental Medicine (CONEM)
I. Horbachevsky Ternopil National Medical University
CONEM Ukraine Natural Drugs Research Group
National University of Pharmacy
Faculty of Medicine
Department of General Medical Practice with a Course of Evidence-Based Medicine
School of Medicine
Department of Pharmacognosy and Botany
CONEM Ukraine Life Science Research Group
Ternopil Ivan Puluj National Technical University

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