The Effect of a Single Dose of Citrulline on the Physical Performance of Soccer-Specific Exercise in Adult Elite Soccer Players (A Pilot Randomized Double-Blind Trial)


Bezuglov E. Morgans R. Lazarev A. Kalinin E. Butovsky M. Savin E. Tzgoev E. Pirmakhanov B. Emanov A. Zholinsky A. Talibov O.
December 2022MDPI

Nutrients
2022#14Issue 23

Purpose: The purpose of this study was to evaluate the effect of a single intake of citrulline at 3 g and 6 g doses in adult elite soccer players performing sport-specific exercise. Materials and Methods: This randomized double-blind placebo-controlled study analyzed 18 soccer players from the top divisions of three European countries. Participants were randomized into three groups of six each and performed a field-based soccer-specific test for 18 min. Comparative analysis of heart rate, fatigue and post-exercise recovery was conducted. Results: There were no statistically significant differences in most of the analyzed parameters, nor at any of the time points for lactate concentration. Players’ RPE exercise test score did not reveal any differences. Conclusions: Neither a single intake of 3 g nor of 6 g of citrulline malate affected physical performance, subjective feelings of fatigue or post-exercise recovery in adult elite soccer players who performed a soccer-specific test.

citrulline , creatine kinase , elite soccer players , fatigue , lactate , performance , rating of perceived exertion , soccer

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Department of Sports Medicine and Medical Rehabilitation, Sechenov First Moscow State Medical University of the Ministry of Health of the Russia, Moscow, 119991, Russian Federation
High Performance Sports Laboratory, Moscow Witte University, Moscow, 115432, Russian Federation
The Academy of the Russian Football Union, Moscow, 115172, Russian Federation
PFC CSKA, Moscow, 125167, Russian Federation
Department of Internal Medicine, Mount Sinai Hospital, Chicago, 60608, IL, United States
Sports Adaptology Lab, Moscow Institute of Physics and Technology (National Research University), Dolgoprudniy, 141701, Russian Federation
Football Club “Rubin”, Kazan, 420036, Russian Federation
Department Neurology and Rehabilitation, Kazan State Medical University, Kazan, 420012, Russian Federation
Higher School of Economics, Moscow, 101000, Russian Federation
Department of Epidemiology, Biostatistics and Evidence-Based Medicine, Faculty of Medicine and Health Care, Al-Farabi Kazakh National University, Almaty, 050040, Kazakhstan
Football Club Kairat, Almaty, 050054, Kazakhstan
“Smart Recovery” Sports Medicine Clinic LLC, Moscow, 121552, Russian Federation
Federal Research and Clinical Center of Sports Medicine and Rehabilitation, Federal Medical Biological Agency, Moscow, 121059, Russian Federation
Department of Internal Medicine, Clinical Pharmacology and Emergency Medicine, Moscow State University of Medicine and Dentistry, Moscow, 127473, Russian Federation

Department of Sports Medicine and Medical Rehabilitation
High Performance Sports Laboratory
The Academy of the Russian Football Union
PFC CSKA
Department of Internal Medicine
Sports Adaptology Lab
Football Club “Rubin”
Department Neurology and Rehabilitation
Higher School of Economics
Department of Epidemiology
Football Club Kairat
“Smart Recovery” Sports Medicine Clinic LLC
Federal Research and Clinical Center of Sports Medicine and Rehabilitation
Department of Internal Medicine

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