Systematisation of biological protectors for managing the metabolic syndrome development

Benberin V.V. Sibagatova A.S. Nagimtayeva A.A. Akhmetova K.M. Voshchenkova T.A.
December 2021 Springer Science and Business Media Deutschland GmbH

Journal of Diabetes and Metabolic Disorders
2021 #20 Issue 2 1449 - 1454 pp.

Background: Metabolic syndrome (MS) is becoming a major health risk in the world. Disorders of homeostasis are a trigger for MS and subsequent cardiometabolic diseases (CMDs). Its physiological role can be supported by biological protectors (BP). The purpose of this study is to develop a BP system for managing the MS development. Methods: Within the framework of the case-control study, 3000 participants aged 20–60 years formed 2 groups: the main group and the control group. Results: The study compared traditional markers of oxidative stress, chronic inflammation, and insulin resistance, which reflect the state of homeostasis. The BP system, proposed based on the concept of maintaining homeostasis, offers the following points for investigating the possibilities of therapeutic intervention: confronting dysregulation of homeostasis, resisting chronic inflammation and oxidative stress, resisting the consequences of disturbed homeostasis. This approach not only contributed to the understanding of general biological processes, but also provided a targeted search and development of BP to maintain the stability of homeostasis with MS. Conclusions: The study results provided insight into new opportunities in the MS management.

Bioprotectors , Cardiometabolic diseases , Homeostasis , Regulation of homeostasis

Text of the article Перейти на текст статьи

Administrative Department, Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, 010000, 80 Mangilik El Ave., Nur-Sultan, Kazakhstan
Sector оf Clinical Research, Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, 010000, 80 Mangilik El Ave., Nur-Sultan, Kazakhstan
Gerontology Centre, Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, 010000, 80 Mangilik El Ave., Nur-Sultan, Kazakhstan

Administrative Department
Sector оf Clinical Research
Gerontology Centre

10 лет помогаем публиковать статьи Международный издатель

Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026