All-fiber label-free optical fiber biosensors: from modern technologies to current applications [Invited]
Bekmurzayeva A. Nurlankyzy M. Abdossova A. Myrkhiyeva Z. Tosi D.
1 March 2024Optica Publishing Group (formerly OSA)
Biomedical Optics Express
2024#15Issue 31453 - 1473 pp.
Biosensors are established as promising analytical tools for detecting various analytes important in biomedicine and environmental monitoring. Using fiber optic technology as a sensing element in biosensors offers low cost, high sensitivity, chemical inertness, and immunity to electromagnetic interference. Optical fiber sensors can be used in in vivo applications and multiplexed to detect several targets simultaneously. Certain configurations of optical fiber technology allow the detection of analytes in a label-free manner. This review aims to discuss recent advances in label-free optical fiber biosensors from a technological and application standpoint. First, modern technologies used to build label-free optical fiber-based sensors will be discussed. Then, current applications where these technologies are applied are elucidated. Namely, examples of detecting soluble cancer biomarkers, hormones, viruses, bacteria, and cells are presented.
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National Laboratory Astana, Nazarbayev University, Astana, 010000, Kazakhstan
School of Engineering and Digital Sciences, Nazarbayev University, Astana, 010000, Kazakhstan
School of Sciences and Humanities, Nazarbayev University, Astana, 010000, Kazakhstan
National Laboratory Astana
School of Engineering and Digital Sciences
School of Sciences and Humanities
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