Synthesis and Antimicrobial Activity of 3D Micro–Nanostructured Diatom Biosilica Coated by Epitaxially Growing Ag-AgCl Hybrid Nanoparticles
Bekissanova Z. Railean V. Wojtczak I. Brzozowska W. Trykowski G. Ospanova A. Sprynskyy M.
January 2024Multidisciplinary Digital Publishing Institute (MDPI)
Biomimetics
2024#9Issue 1
The 3D (three-dimensional) micro–nanostructured diatom biosilica obtained from cultivated diatoms was used as a support to immobilize epitaxially growing AgCl-Ag hybrid nanoparticles ((Ag-AgCl)NPs) for the synthesis of nanocomposites with antimicrobial properties. The prepared composites that contained epitaxially grown (Ag-AgCl)NPs were investigated in terms of their morphological and structural characteristics, elemental and mineral composition, crystalline forms, zeta potential, and photoluminescence properties using a variety of instrumental methods including SEM (scanning electron microscopy), TEM (transmission electron microscopy), EDX (energy-dispersive X-ray spectroscopy), XRD (X-ray powder diffraction), zeta-potential measurement, and photoluminescence spectroscopy. The content of (AgCl-Ag)NPs in the hybrid composites amounted to 4.6 mg/g and 8.4 mg/g with AgClNPs/AgNPs ratios as a percentage of 86/14 and 51/49, respectively. Hybrid nanoparticles were evenly dispersed with a dominant size of 5 to 25 nm in composite with an amount of 8.4 mg/g of silver. The average size of the nanoparticles was 7.5 nm; also, there were nanoparticles with a size of 1–2 nm and particles that were 20–40 nm. The synthesis of (Ag-AgCl)NPs and their potential mechanism were studied. The MIC (the minimum inhibitory concentration method) approach was used to investigate the antimicrobial activity against microorganisms Klebsiella pneumoniae, Escherichia coli, and Staphylococcus aureus. The nanocomposites containing (Ag-AgCl)NPs and natural diatom biosilica showed resistance to bacterial strains from the American Type Cultures Collection and clinical isolates (diabetic foot infection and wound isolates).
Ag-AgCl hybrid nanoparticles , antibacterial activity , diatom biosilica , epitaxial growth nanoparticles , nanoparticles
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Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, 050040, Kazakhstan
Center of Physical-Chemical Methods of Research and Analysis, Almaty, 050012, Kazakhstan
Department of Infectious, Invasive Diseases and Veterinary Administration, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, Gagarina 7, Torun, 87-100, Poland
Interdisciplinary Center for Modern Technologies, Nicolaus Copernicus University in Torun, Wilenska 4, Torun, 87-100, Poland
Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University in Torun, 7 Gagarina Str, Torun, 87-100, Poland
Division of Surface Science, Faculty of Chemical Technology and Engineering, Bydgoszcz University of Science and Technology, Kaliskiego 7, Bydgoszcz, 85-796, Poland
Department of Materials Chemistry, Adsorption and Catalysis, Faculty of Chemistry, Nicolaus Copernicus University in Torun, Gagarina 7, Torun, 87-100, Poland
Faculty of Chemistry and Chemical Technology
Center of Physical-Chemical Methods of Research and Analysis
Department of Infectious
Interdisciplinary Center for Modern Technologies
Department of Environmental Chemistry and Bioanalytics
Division of Surface Science
Department of Materials Chemistry
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