Reactive arthritis following COVID-19: clinical case presentation and literature review


Bekaryssova D. Yessirkepov M. Bekarissova S.
January 2024Springer Science and Business Media Deutschland GmbH

Rheumatology International
2024#44Issue 1191 - 195 pp.

Reactive arthritis (ReA) is a clinical condition typically triggered by extra-articular bacterial infections and often associated with the presence of HLA-B27. While ReA has traditionally been associated with gastrointestinal and genitourinary infections, its pathogenesis involves immune and inflammatory responses that lead to joint affections. The emergence of COVID-19, caused by SARS-CoV-2, has prompted studies of plausible associations of the virus with ReA. We present a case of ReA in a patient who survived COVID-19 and presented with joint affections. The patient, a 31-year-old man, presented with lower limb joints pain. SARS-CoV-2 was confirmed by PCR testing during COVID-19-associated pneumonia. Following a thorough examination and exclusion of all ReA-associated infections, a diagnosis of ReA after COVID-19 was confirmed. In addition, this article encompasses a study of similar clinical cases of ReA following COVID-19 reported worldwide.

Case reports , COVID-19 , Reactive arthritis , SARS-CoV-2

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Department of Biology and Biochemistry, South Kazakhstan Medical Academy, Shymkent, Kazakhstan
Astana Medical University, Astana, Kazakhstan

Department of Biology and Biochemistry
Astana Medical University

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