Exploring the Pharmacological Potential of Lithospermum officinale L.: A Review of Phytochemicals and Ethnomedicinal Uses
Barkizatova G. Turgumbayeva A. Zhakipbekov K. Bekesheva K. Arystanov Z. Arystanova T. Kayupova F. Zhumalina K. Toxanbayeva Z. Ibragimova A. Blinova O. Utegenova G. Iztileu N. Shynykul Z.
April 2024Multidisciplinary Digital Publishing Institute (MDPI)
Molecules
2024#29Issue 8
Exploring phytochemicals from ethnomedicinal plants for pharmacological applications is a promising research area. By studying ethnomedicine, researchers can identify plants used for centuries to treat ailments and investigate their phytochemicals. Consequently, phytochemicals can be isolated, characterized, and tested for pharmacological activities, leading to new drug development. This research also helps preserve traditional knowledge and biodiversity. Lithospermum officinale L., found in Eurasia, Argentina (South), Colombia, and the United States, is valued for its medicinal properties, including anti-inflammatory, antioxidant, and antimicrobial effects. The current review emphasizes L. officinale L. as a significant reservoir of bioactive phytochemicals, with alkaloids, quinones, glucosides, phenolics, flavonoids, and lipids identified as the principal metabolites. It also unveils the unexplored potential of this plant for future research endeavors. Continued research on L. officinale L. can unlock its full potential, providing insights into its medicinal uses and contributing to biodiversity preservation.
alkaloids , biodiversity , ethnomedicine , Lithospermum officinaleL , medicinal plants , phenolics , phytochemicals
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School of Pharmacy, S.D. Asfendiyarov Kazakh National Medical University, Tole Bi St. 94, Almaty, 050000, Kazakhstan
Higher School of Medicine, Al-Farabi Kazakh National University, Almaty, 050040, Kazakhstan
Department of Organization, Management and Economics of Pharmacy and Clinical Pharmacy, Asfendiyarov Kazakh National Medical University, Tole Bi St. 94, Almaty, 050000, Kazakhstan
JSC “Scientific Centre for Anti-Infectious Drug”, Astana, 010000, Kazakhstan
Department of Pharmaceutical Disciplines, Astana Medical University, Beibitshilik Street 49/A, Astana, 010000, Kazakhstan
Department of Pharmacy, Kazakh-Russian Medical University, Abylai Khan St. 51/53, Almaty, 050004, Kazakhstan
Department of Pharmacology, Pharmacotherapy and Clinical Pharmacology, South Kazakhstan Medical Academy, Al Farabi Sq. 1, Shymkent, 160019, Kazakhstan
Department of Organization and Management of Pharmaceutical Business, South Kazakhstan Medical Academy, Alfarabi Sq. 1, Shymkent, 160000, Kazakhstan
School of Pharmacy
Higher School of Medicine
Department of Organization
JSC “Scientific Centre for Anti-Infectious Drug”
Department of Pharmaceutical Disciplines
Department of Pharmacy
Department of Pharmacology
Department of Organization and Management of Pharmaceutical Business
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