High-Sensitivity Electrochemical Detection of Chlorogenic Acid Based on Pt@r-GO@MWCNTs Ternary Nanocomposites Modified Electrodes
Bakytkarim Y. Tursynbolat S. Mukatayeva Zh.S. Tileuberdi Ye. Shadin N.A. Assirbayeva Zh.M. Wang L.S. Zhussupova L.A. Toktarbay Z.
August 2024Engineered Science Publisher
Engineered Science
2024#30
This work reports an electrochemical sensor for high-sensitivity electrochemical determination of chlorogenic acid. The electrochemical sensor was mainly fabricated from Pt@r-GO@MWCNTs ternary nanocomposites prepared by one-pot method, and the modified material structure was characterized by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS) techniques. The electrochemical behavior of chlorogenic acid on Pt@r-GO@MWCNTs/GCE was investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Due to the excellent electrical conductivity and catalytic properties of Pt@r-GO@MWCNTs nanocomposites, compared with bare GCE, Pt@r-GO@MWCNTs/GCE showed stronger electrochemical response signals towards chlorogenic acid. In a 0.1 M PBS buffer solution at pH 6.0 with an enrichment potential of -0.1 V and an enrichment time of 150 s, the linear range of Pt@r-GO@MWCNTs/GCE for the detection of chlorogenic acid was 0.005 ~ 2 µM and 2 ~ 20 µM, and the limit of detection (LOD) was 0.001 µM. In addition, the sensor also has good selectivity, reproducibility, and stability and has been successfully used for the detection of chlorogenic acid in real serum samples with satisfactory results.
Chlorogenic acid , Electrochemical sensor , Nanocompasite , Real sample detection , Selectivity
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Institute of Natural Sciences and Geography, Abai Kazakh National Pedagogical University, 13, Dostyk ave., Almaty, 050010, Kazakhstan
Department of Chemical Processes and Industrial Ecology, Satbayev University, 22, Satbayev street, Almaty, 050013, Kazakhstan
School of Chemistry and Chemical Engineering, South China University of Technology, Guangdong Province, 510641, China
Institute of Natural Sciences, Korkytata Kyzylorda University, Aiteke bi 29A, Kyzylorda, 120014, Kazakhstan
Institute of Ecological Problems, Al-Farabi Kazakh National University, Al-Farabi ave. 71, Almaty, 050040, Kazakhstan
Laboratory of Engineering Profile, Satbayev University, Satbayev St. 22a, Almaty, 050013, Kazakhstan
Institute of Natural Sciences and Geography
Department of Chemical Processes and Industrial Ecology
School of Chemistry and Chemical Engineering
Institute of Natural Sciences
Institute of Ecological Problems
Laboratory of Engineering Profile
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