Long-term effects of endometriosis on oocytes and fertility
Baikoshkarova S.B. Dzhantayeva Z.B. Kulbayeva S.N. Santayev B.A.
2024Kaz Med Print LLP
Reproductive Medicine (Central Asia)
2024#2024Issue 4105 - 111 pp.
Relevance: Recurrent pelvic adhesions in endometriosis are the most common causes of infertility due to dysfunction of the fallopian tubes or ovaries. Despite the number of studies conducted on the effect of ovarian endometriosis on infertility, this question remains essential. In infertile women, the prevalence of the disease endometriosis varies between 20 and 50%, and 35-50% of women with endometriosis are infertile. The relationship between endometriosis and infertility is clinically recognized and well established, which is confirmed in all evidence, although the ultimate causal relationship is controversial. Infertility associated with endometriosis is considered a multifactorial problem due to changes in immunity and genetics that affect not only the fallopian tubes and the embryo transport but also the endometrium. This study was conducted retrospectively to investigate the long-term effects of endometriosis on oocytes and fertility. The study aimed to identify and differentiate the long-term effects of endometriosis on oocytes and fertility. Materials and Methods: We examined and analyzed patients medical history observed in the ECOMED-Shymkent clinic from 2021 to 2023 and registered in this institution. Results: Our analysis shows the effect of endometriosis on oocytes, oocyte quality, follicle formation, and fertilization. The results of this scientific analysis can be used to manage, diagnose, and treat women with endometriosis, solving their infertility problems. Conclusion: At the initial diagnosis of endometriosis, treatment should be carried out throughout the patients life, taking into account the potential impact of the disease on the patients reproductive life. In addition, we must consider changes in the reproductive habits of modern society, such as the postponement of the age of first pregnancy among the modern female population. Patients should be treated with appropriate treatment and supervision, and we should identify patients who benefit from fertility maintenance as early as possible. Depending on the effect of endometriosis on the reproductive state and the progressive nature of the pathology in infertile women diagnosed with endometriosis, we must implement all strategies (medical, surgical, CT) at the appropriate time and in ways according to the characteristics of the patient. Future endometriosis studies should evaluate the cost/benefits of fetal circulatory procedures and stimulation protocols.
assisted reproductive technologies , endometriosis , in vitro fertilization , infertility
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Biological Sciences, Embryologist, ECOMED clinic group, Almaty, Kazakhstan
ECOMED Shymkent Clinic, Shymkent, Kazakhstan
Obstetrics and Gynecology Department, South Kazakhstan Medical Academy, Shymkent, Kazakhstan
Biological Sciences
ECOMED Shymkent Clinic
Obstetrics and Gynecology Department
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