Effects of endometriosis on oocytes and fertilization: A literature review
Baikoshkarova S.B. Dzhantayeva Z.B. Kulbayeva S.N. Santayev B.A.
2024Kaz Med Print LLP
Reproductive Medicine (Central Asia)
2024#2024Issue 323 - 28 pp.
Relevance: Endometriosis is a gynecological disease characterized by developing endometrial stroma and glands outside the uterine cavity, leading to various lesions and a chronic inflammatory reaction. The frequency and prevalence of infertility is 40-50%. The prevalence of this pathology among women of reproductive age is up to 15%. The pathogenesis of this disease has not been thoroughly studied to date and requires careful study. Several studies have reported adverse effects of in vitro fertilization (IVF) after the reproductive results of women were associated with endometriosis, but no discrepancy with other diseases was found. The reasons for these differences, whether endometriosis affects the quality of eggs and whether embryonic miscarriage is a frequently diagnosed gynecological condition in endometriosis lesions, have not been clarified. The study aimed to determine the effect of endometriosis on oocytes and fertilization. Materials and Methods: We conducted a search and study of articles published in English in the period from 2014 to 2024 in the databases PubMed, Web of Science, Embase, and Google Scholar. Our study Results: The analysis revealed the effect of endometriosis on oocytes, egg quality, folliculogenesis, and fertilization. The results of this scientific analysis can be applied to the management of women with different localizations of endometriosis, diagnostic and therapeutic measures, and the solution of infertility in this contingent of women. Conclusion: Assisted reproduction methods, including superovulation with in vitro fertilization or intrauterine insemination, are effective treatment alternatives. In women with this pathology, there is a decrease in ovarian reserve, which requires careful selection of therapy and timely assistance with the help of high-tech reproductive technologies and an individual approach.
assisted reproductive technologies (ART) , endometriosis , fertilization , in vitro fertilization (IVF) , infertility , oocytes
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ECOMED Clinic Group, Almaty, Kazakhstan
ECOMED Shymkent Clinic, Shymkent, Kazakhstan
South Kazakhstan Medical Academy, Shymkent, Kazakhstan
ECOMED Clinic Group
ECOMED Shymkent Clinic
South Kazakhstan Medical Academy
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