Comparison of clinical outcomes in idiopathic pulmonary fibrosis patients with and without hiatal hernia

Hiatal hernisi olan ve olmayan idiyopatik pulmoner fibrozis hastalarında klinik sonuçların karşılaştırılması
Ayten Ö. Okutan O. Kalbaran Kismet G. Türkoğlu Ö. Samanci C. Çalişkan T. Canoğlu K.
2022 Ankara University

Tuberkuloz ve Toraks
2022 #70 Issue 2 113 - 121 pp.

Comparison of clinical outcomes in idiopathic pulmonary fibrosis patients with and without hiatal hernia Introduction: Idiopathic pulmonary fibrosis (IPF) is a progressive disease of unknown etiology with an unpredictable course. We aimed to investigate the effects of the presence of hiatal hernia (HH) and its consequences on the clinical manifestation of IPF. Materials and Methods: Patients diagnosed with IPF with or without hiatal hernia were retrospectively compared in terms of clinical findings, total fibro-sis scores (TFS), and lung function in the interstitial lung diseases (ILD) outpatient clinic. Results: A total of 142 IPF patients were included in the study. HH was detec-ted in 62.7% (n= 89) of the patients. There was no statistically significant difference between IPF patients with or without HH in terms of age, gender, smoking history, and anti-reflux drug use (p> 0.05). There was no statistically significant difference between IPF patients with or without HH in terms of symptoms such as dyspnea, cough, regurgitation, heartburn, nausea, dyspha-gia, chest pain, and hoarseness (p> 0.05). In addition, no statistically significant difference was found between IPF patients with or without HH in terms of mortality rate, survival time after diagnosis, and exacerbations (p> 0.05). Six-minute walking distance and SpO₂ change, percentage of predicted for-ced vital capacity (FVC) value, and percentage of predicted diffusing capacity for carbon monoxide (DLCO) value did not differ significantly between the groups (p> 0.05). There was no statistically significant difference between the groups in terms of total fibrosis score (p= 0.668). Conclusion: According to the results of this study, 62.7% (n= 89) of IPF patients had HH, and there was no difference in clinical outcomes, TFS, and pulmonary functions between IPF patients with or without HH.

hiatal hernia , Idiopathic pulmonary fibrosis , pulmonary functions , total fibrosis score

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Clinic of Pulmonary Medicine, Sultan, Kazakhstan
Abdulhamid Han Training and Research Hospital, İstanbul, Turkey
Department of Radiology, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey

Clinic of Pulmonary Medicine
Abdulhamid Han Training and Research Hospital
Department of Radiology

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