Electrosteric forces drive the stability and antibacterial function of polysaccharide-stabilized silver nanoparticles


Asserzhanov D.K. Grachev V. Hornok V. Klivenko A.N. Abdullina E.S. Kassymova Z.S. Szilagyi I.
1 January 2026Elsevier B.V.

Journal of Molecular Liquids
2026#441

Aggregation dynamics of silver nanoparticles (AgNPs) is one of the key factors determining their application in biomedicine, ecology and industry. In this work, AgNPs are synthesized by the method of green chemical reduction using polysaccharides – carboxymethylcellulose, alginate and chitosan - as reducing agents and stabilizers. Colloidal stability and interfacial behavior of AgNPs were investigated in the presence of mono-, di- and trivalent ions (Na+, Ca2+, La3+; Cl, SO42− and PO43−). The aggregation mechanism was qualitatively in line with the prediction of the DLVO theory, balancing electrical double layer repulsion and van der Waals attraction, however, variations in the resistances against salt-induced aggregation shed light on the presence of electrosteric interparticle forces. Antibacterial activity of stabilized AgNPs against Moraxella bovoculi - the causal agent of infectious cattle keratoconjuctivitis - was investigated. The synthesized nanoparticles demonstrated high antibacterial activity, while maintaining stability suggesting their potential in veterinary medicine and food safety, where processable dispersions of homogeneously distributed particles possessing high surface area are needed for the efficient therapies. Copyright

Alginate , Antibacterial activity , Carboxymethylcellulose , Chitosan , Colloidal stability , Silver

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Department of Chemistry and Ecology, Research School of Physical and Chemical Sciences, Shakarim University, 20A Glinka street, Semey, 071410, Kazakhstan
MTA-SZTE Momentum Biocolloids Research Group, Department of Physical Chemistry and Materials Science, Interdisciplinary Centre of Excellence, University of Szeged, 1 Rerrich Bela square, Szeged, 6720, Hungary

Department of Chemistry and Ecology
MTA-SZTE Momentum Biocolloids Research Group

10 лет помогаем публиковать статьи Международный издатель

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