Microwave activation of isovaleric acid monoglyceride synthesis and its antimicrobial activity
Appazov N.O. Syzdykbayev M.I. Appaz A.N. Nazarov E.A. Darmagambet K.Kh. Balykbayeva G.T. Abzhalelov B.B. Askarova G.Sh. Kim Yu.A.
2024Bulgarska Akademiya na Naukite
Bulgarian Chemical Communications
2024#56Issue 19 - 13 pp.
The article describes the microwave synthesis of isovaleric acid monoglyceride by the isopropylidene method using microwave-assisted synthesis. The yield of the target product was 94%. The resulting compound was characterized by 1H NMR, 13C NMR, IR spectroscopy and elemental analysis. The resulting product was studied for antibacterial and antifungal activity. It was found that isovaleric acid monoglyceride has pronounced antibacterial activity against Pseudomonas aeruginosa and moderate antifungal activity against Candida albicans.
antibacterial , antifungal activity , isopropylidene protection , isovaleric acid monoglyceride , microwave-assisted synthesis
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Korkyt Ata Kyzylorda University, 29A Ayteke bi Str., Kyzylorda, Kazakhstan
Limited Liability Partnership “DPS-Kyzylorda”, 11A Amangeldi Str., Kyzylorda, Kazakhstan
Nazarbayev Intellectual School Chemical-Biological Direction in Kyzylorda, 6 Sultan Beybars Str., Kyzylorda, Kazakhstan
Institute of Cell Biophysics of the Russian Academy of Sciences, 3 Institutskaya Str., Pushchino, Moscow Region, Russian Federation
Korkyt Ata Kyzylorda University
Limited Liability Partnership “DPS-Kyzylorda”
Nazarbayev Intellectual School Chemical-Biological Direction in Kyzylorda
Institute of Cell Biophysics of the Russian Academy of Sciences
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