Comparative Analysis of the Polymorphism of the Casein Genes in Camels Bred in Kazakhstan

Amandykova M. Dossybayev K. Mussayeva A. Bekmanov B. Saitou N.
April 2022 MDPI

Diversity
2022 #14 Issue 4

Caseins play an important role in determining the technological properties and quantitative characteristics of camel milk. To date, only a few studies on the genetic polymorphism of casein genes have been reported in the camel populations of Kazakhstan. Therefore, this work aimed to identify the genetic polymorphism level of casein genes among camel populations of the Almaty region of Kazakhstan. The PCR-RFLP method was used for this purpose and the following genotypes were revealed as a result: CSN3 gene—CC, CT, TT, where the T allele predominated in all populations, with a frequency of 0.60; CSN2 gene—AA, AG, GG, with the predomination of A allele (0.64); and CSN1S1 gene—GG and GT, with the predomination of G allele (0.94). Statistical analysis was carried out using the POPGENE and GenAlEx software. The χ2 values were equal to 12.1 (CSN3), 8.6 (CSN2), and 14.5 (CSN1S1). As a result, three out of 53 animals were designated as the “core” of the population—animals with the desired genotypes: CC genotype for the CSN3 gene and AA genotype for the CSN2 gene. Such animals can be selected for further use with an increase in the number of livestock with high productivity rates.

camel , casein genetic variability , CSN1S1 , CSN2 , CSN3 , milk productivity , PCR-RFLP

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Faculty of Biology and Biotechnology, Al-Farabi Kazakh National University, Al-Farabi Ave., 71, Almaty, 050040, Kazakhstan
Laboratory of Genetics and Cytogenetics, Institute of Genetics and Physiology, SC MES RK, Al-Farabi Ave., 93, Almaty, 050060, Kazakhstan
Division of Population Genetics, National Institute of Genetics, 1111 Yata Shizuoka, Mishima, 411-8540, Japan

Faculty of Biology and Biotechnology
Laboratory of Genetics and Cytogenetics
Division of Population Genetics

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