Minimally invasive technologies in stabilizing the respiratory status of preterm infants: A literature review


Alimukhamedov U.R. Bozhbanbayeva N.S. Urazbayeva G.G. Tolykkbayev T.Zh. Tastimirov M.Zh.
2025Kaz Med Print LLP

Reproductive Medicine (Central Asia)
2025#2025Issue 167 - 75 pp.

Relevance: The high incidence of premature infants remains a serious public health problem, as they require specialized care. Stabilizing the condition in the first minutes of life is critical for survival and health. This literature review focuses on the stabilization of the respiratory status of premature infants using minimally invasive technologies. It has been established that such methods as heated and humidified high-flow nasal cannula, LISA (less invasive surfactant administration), lung ultrasound, POCUS (Point-of-Care Ultrasound), cardiac ultrasound, electrocardiography, and nitric oxide inhalation help reduce respiratory complications and improve long-term outcomes. The study aimed to analyze the literature and comment on current approaches to stabilization of the respiratory status using minimally invasive technologies in premature infants soon after birth, as well as to identify insufficiently studied aspects of their use in neonatal practice. Materials and Methods: A review of scientific sources from PubMed, Scopus, Web of Science, and eLibrary for 2014-2024 was conducted. Studies evaluating the effectiveness of minimally invasive respiratory support methods were selected. Results: The analysis confirmed that minimally invasive technologies contribute to prolonged oxygenation, decreased bronchopulmonary dysplasia and intraventricular hemorrhage incidence, and accurate diagnosis of cardiorespiratory disorders. Conclusion: Using minimally invasive technologies reduces the need for invasive interventions, increases survival, and improves long-term outcomes in premature infants, which requires an individualized approach.

cardiac ultrasound , inhaled nitric oxide , LISA , lung ultrasound , minimally invasive technologies , preterm infants , respiratory failure

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Neonatology Department, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Neonatology Unit, Scientific Center for Obstetrics, Gynecology, and Perinatology, Almaty, Kazakhstan
Zhambyl regional perinatal center of the Akimat of Zhambyl region Health Department, Taraz, Kazakhstan

Neonatology Department
Neonatology Unit
Zhambyl regional perinatal center of the Akimat of Zhambyl region Health Department

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