Fallopia convolvulus (L.) Á. Löve: Review of traditional use, phytochemistry and pharmacology
Akmuratkyzy Z. Turgumbayeva A. Kulbayeva M. Azembayev A. Nurgaliyeva Z. Seisebayeva R. Kulniyazova G. Jaxalykova K. Karin B. Aubakirova Z. Doskenova B. Zhanaliyeva M. Zharikassimov R. Bukeyeva Z.
2025Pensoft Publishers
Pharmacia
2025#721 - 12 pp.
Fallopia convolvulus (L.) Á. Löve, a widely distributed species of the Polygonaceae family, has long been valued in traditional medicine for its diverse therapeutic applications. This review investigates its phytochemical composition, traditional uses, and pharmacological potential, placing the plant in the broader context of natural product research. Bioactive compounds such as flavonoids, anthraquinones, steroids, and phenolic acids, which exhibit antioxidant, anti-inflammatory, antimicrobial, and anticancer activities, are compiled and analyzed. Modern techniques have identified novel compounds like falloconvolin A and B, as well as compounds with estrogenic and neuroprotective properties. To support this analysis, information was sourced from ethnobotanical, phytochemical, pharmacological, and clinical studies, utilizing databases like PubMed, Science Direct, and ResearchGate. This comprehensive analysis underscores the importance of further research to elucidate the mechanisms of action of its bioactive constituents and to explore its potential for pharmaceutical innovation. Fallopia convolvulus represents a promising, sustainable resource for developing novel therapeutic agents, bridging traditional medicine with modern science. Copyright Akmuratkyzy Z et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Fallopia convolvulus , flavonoids , pharmacological activities , phytochemicals , Polygonaceae , traditional medicine
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Higher School of Medicine, Al-Farabi Kazakh National University, Almaty, 050040, Kazakhstan
Faculty of Biology and Biotechnology, Department of Biophysics, Biomedicine and Neuroscience, Al-Farabi Kazakh National University, Almaty, 050040, Kazakhstan
JSC “Scientific Center for Anti-Infectious Drugs”, Almaty, 050000, Kazakhstan
Department of Organization, Management and Economics of Pharmacy and Clinical Pharmacy, JSC “S.D. Asfendiyarov Kazakh National Medical University”, Almaty, 050000, Kazakhstan
School of Pediatrics, Department of Outpatient Pediatrics, JSC “S.D. Asfendiyarov Kazakh National Medical University”, Almaty, 050000, Kazakhstan
JSC “S.D. Asfendiyarov Kazakh National Medical University”, Almaty, 050000, Kazakhstan
Department of Neonatology, NJSC “Astana Medical University”, Astana, 010000, Kazakhstan
Department of Medical sciences, NJSC “Astana Medical University”, Astana, 010000, Kazakhstan
Department of Pediatric Diseases with Courses in Pulmonology and Nephrology, NJSC “Astana Medical University”, Astana, 010000, Kazakhstan
Department of Human Anatomy Republic of Kazakhstan, NJSC “Astana Medical University”, Astana, 010000, Kazakhstan
Department of Surgical Diseases with a Course of Cardio-thoracic Surgery and Maxillofacial Surgery, NJSC “Astana Medical University”, Astana, 010000, Kazakhstan
Research Institute of Preventive Medicine named after Academician E.D.Dalenov, NJSC “Astana Medical University”, Astana, 010000, Kazakhstan
Higher School of Medicine
Faculty of Biology and Biotechnology
JSC “Scientific Center for Anti-Infectious Drugs”
Department of Organization
School of Pediatrics
JSC “S.D. Asfendiyarov Kazakh National Medical University”
Department of Neonatology
Department of Medical sciences
Department of Pediatric Diseases with Courses in Pulmonology and Nephrology
Department of Human Anatomy Republic of Kazakhstan
Department of Surgical Diseases with a Course of Cardio-thoracic Surgery and Maxillofacial Surgery
Research Institute of Preventive Medicine named after Academician E.D.Dalenov
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