Synthesis of Functionally Substituted Dithiocarbamate Derivatives as Potential Plant Growth Regulators
Akimbayeva N. Zhumanova N. Myrzakhmetova N. Dzhiembaev B. Kuandykova A. Diyarova B. Yerezhepova A. Kudaibergenova G.
September 2025Engineered Science Publisher
ES Food and Agroforestry
2025#21
Dithiocarbamates, as sulfur-containing compounds, possess diverse biological activities and have promising applications in agriculture as plant growth regulators (PGRs). In this study, we report the first synthesis of a novel series of functionally substituted potassium and sodium dithiocarbamate derivatives via aminomethylation of phenylacetylene followed by dithiocarbamate formation. Structural confirmation was achieved using Infrared (IR), proton and carbon-13 Nuclear Magnetic Resonance (1H, and13C NMR) spectroscopy. Biological assays on wheat and barley seeds demonstrated that specific derivatives significantly enhanced germination and seedling vigor. Notably, potassium and sodium dithiocarbamates at concentrations of 0.001% and 0.0001% achieved laboratory germination rates of up to 99.3%, exceeding both the untreated control (96.0%) and the commercial reference treatment (94.0%). In addition, microbial contamination was markedly suppressed; for example, compound No. 8 (sodium, 0.01%) reduced the percentage of infected wheat seeds to 30.0%, compared to 95.3% in the control. These results indicate that the synthesized dithiocarbamate derivatives are promising eco-friendly candidates for enhancing crop establishment and integrated seed protection.
Aminomethylation , Biological activity , Dithiocarbamates , Plant growth regulators , Seed germination
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Department of Chemistry, Institute of Natural Sciences, Kazakh National Woman’s Teacher Training University, Almaty, 700420, Kazakhstan
Department of Chemistry
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026