The distribution and prevalence of high-risk hpv genotypes other than hpv-16 and hpv-18 among women attending gynecologists’ offices in Kazakhstan

Aimagambetova G. Babi A. Issanov A. Akhanova S. Udalova N. Koktova S. Balykov A. Sattarkyzy Z. Abakasheva Z. Azizan A. Chan C.K. Issa T.
August 2021 MDPI AG

Biology
2021 #10 Issue 8

Cervical cancer represents a great burden to public health of women. This study aimed to obtain a nationwide genotyping survey and analysis of high risk-HPV including those that are caused by HPV types other than HPV-16 and HPV-18, among women in Kazakhstan. This study was conducted based on the collection of survey and cervical swabs of 1645 women across the country. The samples were genotyped for high-risk HPV types based on real-time PCR methods. Collected data was analyzed with the focus on high-risk HPV types other than HPV-16 and-18. Infection was present in 22% of women who participated in the study. The most prevalent types were HPV-31 among single infections and HPV-68 among multiple infections. Conclusively, despite the lack of attention high-risk HPV types beyond HPV-16 and-18 get in attempts of cervical cancer prevention in Kazakhstan, their prevalence is high and plays a large role in cervical cancer epidemiological situation.

Cervical cancer , High-risk HPV , HPV , HPV epidemiology , Kazakhstan

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Department of Biomedical Sciences, School of Medicine, Nazarbayev University, Nur-Sultan, 010000, Kazakhstan
Department of Medicine, School of Medicine, Nazarbayev University, Nur-Sultan, 010000, Kazakhstan
Obstetrics and Gynecology Department, Keruen Medicus Clinic, Almaty, 050040, Kazakhstan
Obstetrics and Gynecology Department, East Kazakhstan Regional Hospital, Oskemen, 07000, Kazakhstan
Regional Perinatal Center, Altynsarin 3, Aktobe, 030006, Kazakhstan
Obstetrics and Gynecology Department, City polyclinic #6, Nur-Sultan, 010000, Kazakhstan
Gynecology Department, Daliya Clinic, Pavlodar, 140013, Kazakhstan
Department of Basic Sciences, College of Osteopathic Medicine, Touro University Nevada, Henderson, 89014, NV, United States
Department of Biology, College of Science and Technology, Wenzhou-Kean University, Wenzhou, 325000, China

Department of Biomedical Sciences
Department of Medicine
Obstetrics and Gynecology Department
Obstetrics and Gynecology Department
Regional Perinatal Center
Obstetrics and Gynecology Department
Gynecology Department
Department of Basic Sciences
Department of Biology

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