Comparison of diagnostic accuracy and acceptability of self-sampling devices for human Papillomavirus detection: A systematic review
Aimagambetova G. Atageldiyeva K. Marat A. Suleimenova A. Issa T. Raman S. Huang T. Ashimkhanova A. Aron S. Dongo A. Iztleuov Y. Shamkeeva S. Azizan A.
February 2024Elsevier Inc.
Preventive Medicine Reports
2024#38
Objective: Cervical cancer screening coverage remains low in many countries worldwide. Self-sampling approach for cervical cancer screening has a good potential to improve the screening coverage. This study aims to compare different types of HPV self-sampling devices for cervical cancer screening to identify the most accurate and acceptable device(s). Methods: A systematic review was performed on data extracted from all studies specific to HPV self-sampling devices by searching relevant articles in PubMed, Google Scholar, Scopus, Web of Science, ScienceDirect, Cochrane Library, and EBSCO published from 2013 to October 2023. The study was registered in PROSPERO (CRD42022375682). Results: Overall, 70 papers met the eligibility criteria for this systematic review and were included in the analysis: 22 studies reported self-sampling devices diagnostic accuracy, 32 studies reported self-sampling devices acceptability and 16 studies reported both (accuracy and acceptability). The most popular self-sampling devices were Evalyn Brush, FLOQ Swab, Cervex-Brush, and Delphi Screener. Out of overall 38 studies analyzing self-sampling devices’ diagnostic accuracy, 94.7% of studies reported that self-collected specimens provided sensitivity and specificity comparable with clinician-collected samples; acceptability of Evalyn Brush, FLOQ Swab, Delphi Screener, and Colli-Pee, varied between 84.2% and 100%. Conclusion: The self-sampling approach has a good potential to increase cervical cancer screening coverage. Evalyn Brush, Cervex-Brush, FLOQ Swab, and Delphi Screener self-sampling devices for HPV detection were the most commonly utilized and found to be the most accurate, and patient-acceptable. HPV detection accuracy using these self-sampling devices had no significant difference compared to the sampling performed by healthcare providers.
Cervical cancer screening , Cervical self-sampling , HPV , HPV self-sampling , HPV self-sampling device , Self-sampling , Self-sampling device
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Department of Surgery, School of Medicine, Nazarbayev University, Astana, 010000, Kazakhstan
Department of Medicine, School of Medicine, Nazarbayev University, Astana, 010000, Kazakhstan
Clinical Academic Department of Internal Medicine, CF “University Medical Center”, Astana, 10000, Kazakhstan
Department of Obstetrics and Gynecology #1, NJSC “Astana Medical University”, Astana, 010000, Kazakhstan
Kazakh National Institute of Oncology and Radiology, Almaty, Kazakhstan
School of Medicine, Nazarbayev University, Astana, 010000, Kazakhstan
College of Osteopathic Medicine, Touro University Nevada, Henderson, NV, United States
Department of Clinical Medicine, School of Medicine, Al Farabi University, Almaty, Kazakhstan
Medical Center, Marat Ospanov West-Kazakhstan Medical University, Aktobe, 030000, Kazakhstan
Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University Hospital, Leipzig, 04103, Germany
Department of Surgery
Department of Medicine
Clinical Academic Department of Internal Medicine
Department of Obstetrics and Gynecology #1
Kazakh National Institute of Oncology and Radiology
School of Medicine
College of Osteopathic Medicine
Department of Clinical Medicine
Medical Center
Institute of Laboratory Medicine
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