Hypopharynx Cancer Incidence in Kazakhstan: 2017-2021
Ahmedin D. Makishev A. Telmanova Z. Turebayev D. Tarzhanova D. Shelestyuk A. Lyust V. Kassenova D. Grigorevskiy V. Igissinova G. Bilyalova Z. Syzdykov N. Muratbekova S. Igissin N.
2023Asian Pacific Organization for Cancer Prevention
Asian Pacific Journal of Cancer Prevention
2023#24Issue 124043 - 4051 pp.
Objective: The article studies the geographical features of the incidence of hypopharynx cancer (HPC) in Kazakhstan. Methods: The retrospective study was done for the period 2017-2021. Descriptive and analytical methods of ecoepidemiology were used. Crude (CR), age-specific (ASIR), age-standardized (ASR), equalized incidence rates and approximation were calculated. The dynamics of indicators was investigated using component analysis according to methodological recommendations. The method of drawing up a cartogram based on the determination of the standard deviation (σ) from the mean (x) was applied. Result: During the study period, 814 new cases of HPC were registered. The incidence rate decreased from 0.898 (2017) to 0.895 in 2021 and the overall decline was 0.003 per 100,000 population, including due to the age structure - ΣΔA=+0.04, due to the risk of acquiring illness - ΣΔR=-0.05 and their combined effect - ΣΔRA=+0.01. The component analysis revealed that the increase in the number of patients with HPC was mainly due to the growth of the population (ΔP=+37.0%), changes in its age structure (ΔA=+106.1%) and changes associated with the risk of acquiring illness (ΔR=-133.4%). The cartograms were allocated according to the following criteria: low - up to 0.730/0000, average - from 0.73 to 1.180/0000, high - above 1.180/0000. The results of the spatial assessment showed the highest levels of HPC incidence in following regions: Atyrau (1.960/0000) and West Kazakhstan (1.580/0000). Conclusion: Thus, this is the first epidemiological study of HPC, which assessed the role of the influence of various factors, including demographic and risk of acquiring illness, on the dynamics of incidence, taking into account gender differences and geographical variability.
component analysis , hypopharynx cancer , incidence , Kazakhstan
Text of the article Перейти на текст статьи
Department of Oncology, Astana Medical University, Astana, Kazakhstan
Central Asian Institute for Medical Research, Astana, Kazakhstan
Department of Surgical Diseases with courses of Angiosurgery and Plastic Surgery, Astana Medical University, Astana, Kazakhstan
Department of General Pharmacology, Astana Medical University, Astana, Kazakhstan
Department of Obstetrics and Gynecology No. 1, Astana Medical University, Astana, Kazakhstan
Department of ENT Diseases, Astana Medical University, Astana, Kazakhstan
Department of Oncology, Kazakh National Medical University Named After SD Asfendiyarov, Almaty, Kazakhstan
Health Department of the Akmola region, Kokshetau, Kazakhstan
Higher School of Medicine, Kokshetau University named after Sh. Ualikhanov, Kokshetau, Kazakhstan
Research Institute of Life and Health Sciences, Higher School of Medicine, Kokshetau University named after Sh. Ualikhanov, Kokshetau, Kazakhstan
Asian Pacific Organization for Cancer Prevention, Bishkek, Kyrgyzstan
Department of Oncology
Central Asian Institute for Medical Research
Department of Surgical Diseases with courses of Angiosurgery and Plastic Surgery
Department of General Pharmacology
Department of Obstetrics and Gynecology No. 1
Department of ENT Diseases
Department of Oncology
Health Department of the Akmola region
Higher School of Medicine
Research Institute of Life and Health Sciences
Asian Pacific Organization for Cancer Prevention
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026