Assessment of the clinical significance of hypomagnesemia in pregnant women: A literature review
Adyrbekova A.K. Isenova S.Sh. Kazybaeva A.S. Shukirbaeva A.S.
2024Kaz Med Print LLP
Reproductive Medicine (Central Asia)
2024#2024Issue 274 - 79 pp.
Relevance: Studying magnesium deficiency during pregnancy is crucial due to its extensive impact on maternal health and fetal development. Magnesium deficiency has been linked to adverse outcomes such as premature birth, gestational diabetes, and hypertension. Understanding the mechanisms and consequences of hypomagnesemia is vital in healthcare, as it can lead to new preventive and treatment strategies, improving pregnancy outcomes and the health of future generations. The study aimed to summarize current data on the clinical significance of magnesium deficiency, as reported in journals focused on obstetrics and perinatology. Materials and Methods: A literature review was conducted using PubMed, Scopus, Medline, and Google Scholar databases, covering domestic and international studies from the past decade (2013-2023). Keywords used in the search included «magnesium», «pregnancy», «magnesium deficiency», and «trace elements», employing MESH for keyword searches. Results: The analysis highlights the essential role of magnesium in pregnancy and childbirth outcomes, as well as fetal growth, development, and postnatal health. Magnesium deficiency during pregnancy can have serious repercussions for both mother and fetus. This condition is recognized in the ICD-10 under E61.3 «magnesium deficiency». Magnesium is crucial for various biological processes, including muscle contraction, cardiac function, blood pressure regulation, and metabolism. During pregnancy, the increased magnesium requirement is essential for fetal development and maternal health. Insufficient magnesium intake can lead to complications, but a balanced diet with magnesium-rich foods like nuts, seeds, greens, grains, and beans can prevent deficiency and related pregnancy issues. Conclusion: Pregnant women are at a heightened risk of magnesium deficiency, potentially leading to significant fetal developmental issues and increased rates of premature birth. Current literature indicates that low maternal magnesium levels during pregnancy should be considered a factor in the fetal programming of adult diseases.
magnesium , magnesium deficiency , pregnancy , trace elements
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Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Obstetrics and Gynecology Department with a course in Medical Genetics, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Asfendiyarov Kazakh National Medical University
Obstetrics and Gynecology Department with a course in Medical Genetics
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026