New Arylhalo-Derivatives of Grosshemin


Adekenov S.M. Kishkentayeva A.S. Khasenova A.B. Shul’ts E.E. Gatilov Y.V. Bagryanskaya I.Y.
July 2021Springer

Chemistry of Natural Compounds
2021#57Issue 4685 - 690 pp.

Pd-catalyzed arylation of grosshemin by iodoarenes synthesized products with an exocyclic C-11,13 double bond in the (E)- and (Z)-configurations. The structures of four compounds were established by X-ray crystal structure analyses. The antibacterial activity and cytotoxicity of the new compounds were assessed.

antibacterial activity , cytotoxicity , grosshemin , Heck reaction , sesquiterpenoids , X-ray crystal structure analysis

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International Scientific-Production Holding Phytochemistry, 4 M. Gazalieva St., Karaganda, 100009, Kazakhstan
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 9 Prosp. Lavrent’eva, Novosibirsk, 630090, Russian Federation

International Scientific-Production Holding Phytochemistry
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry

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