Isoprenoids from Rhaponticum carthamoides (Willd.) Iljin and Rhaponticum serratuloides (Georgi.) Bobr
Adekenov S.M.
20 June 2024al-Farabi Kazakh State National University
International Journal of Biology and Chemistry
2024#17Issue 189 - 101 pp.
The article presents the results of a chemical study of Rhaponticum carthamoides (Willd.) Iljin. and Rhaponticum serratuloides (Georgi.) Bobr., which are of interest as sources of new adaptogenic, anabolic, and antiparasitic drugs; a method for complex chemical processing of the raw materials of the above-mentioned plants has been proposed. The structure of new sesquiterpene lactones raposerine, raserolide, 15-deacetylraposerine, and raserine has been isolated and established. The content of pharmacologically active ecdysterone in various organs of the studied Rhaponticum species is discussed according to the phenological phases of plant development. The antiparasitic, antiviral activity and cytotoxicity of the isolated compounds were determined.
ecdysterone , isoprenoids , Rhaponticum carthamoides (Willd.) Iljin. , Rhaponticum serratuloides (Georgi.) Bobr. , sesquiterpene lactones
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Joint-stock company “International Research and Production Holding “Phytochemistry”, Karaganda, Kazakhstan
Joint-stock company “International Research and Production Holding “Phytochemistry”
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