Genotyping of Crimean-Congo haemorrhagic fever virus circulating in South Kazakhstan

Abuova G.N. Karan L.S. Pshenichnaya N.Yu. Berdalieva F.A. Aliev D.S. Sadyhova D.К. Polukchi T.V. Nurmagambet S.D. Lizinfeld I.A. Akimkin V.G.
2022 Dynasty Publishing House

Infektsionnye Bolezni
2022 #20 Issue 4 49 - 54 pp.

Southern regions of Kazakhstan are endemic for Crimean-Congo haemorrhagic fever (CCHF). The virus causing CCHF has several genotypes that prevail in certain geographical areas. Limited information on CCHF circulating in South Kazakhstan necessitates careful investigation of this virus with phylogenetic analysis of viral RNA in CCHF patients from Turkestan region and Shymkent. Objective. To analyze the genotypes of CCHF viruses circulating in Turkestan region and Shymkent. Materials and methods. We examined 12 serum samples from CCHF patients, in whom specific anti-CCHF IgM had been detected. Results. CCHF RNA was found in 10 out of 12 samples tested. Comparison of the obtained CCHF sequences with those from the GenBank demonstrated that isolates from Turkestan region and Shymkent belong to the genetic group Asia 1 and the reassortant Asia 1 and Asia 2. Conclusion. We performed the first phylogenetic analysis of CCHF strains circulating in Turkestan region of Kazakhstan and Shymkent and found that they belong to the genetic group Asia 1 and the reassortant Asia 1 and Asia 2.

CCHF , Crimean-Congo hemorrhagic fever , endemic area , genotypes of the CCHF virus , genotyping , South Kazakhstan

Text of the article Перейти на текст статьи

South Kazakhstan Medical Academy, Shymkent, Kazakhstan
Central Research Institute of Epidemiology of The Federal Service on Customers Rights Protection and Human Well-being Surveillance, Moscow, Russian Federation

South Kazakhstan Medical Academy
Central Research Institute of Epidemiology of The Federal Service on Customers Rights Protection and Human Well-being Surveillance

10 лет помогаем публиковать статьи Международный издатель

Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026