Clinical and laboratory COVID-19 features in hospitalized patients with concomitant diabetes mellitus type 2: A retrospective study

Abilbayeva A. Tarabayeva A. Idrisova G. Abdrakhmanova A. Sadykova A. Yegemberdiyeva R. Duisenova A.
2022 National Scientific Medical Center

Journal of Clinical Medicine of Kazakhstan
2022 #19 Issue 6 83 - 88 pp.

Objective: To investigate the prevalence of diabetes mellitus in comorbidity structures and its effect on the clinical course in hospitalized COVID-19 patients in south region of Kazakhstan. Material and methods: A retrospective analysis of data from 918 patients with COVID-19 treated at the City Clinical Infectious Diseases Hospital was carried out. Pearsons Chi-square test and Students t-test were conducted. Results: In Kazakhstan, diabetes mellitus occupies the second position in the structure of comorbidities in patients with COVID-19 with a share of 20%. Diabetes mellitus in patients most often occurs in combination with cardiovascular diseases and arterial hypertension (20.3% and 16.3%, respectively). Combination of diabetes mellitus, arterial hypertension and other diseases was detected in 72.4% of patients. Combination of diabetes mellitus, cardiovascular and other diseases was detected in 32.5%. In diabetes mellitus patients, COVID-19 was more severe, the hospital stay was longer, and patients over 60 years of age suffered. These patients had a combination of diabetes mellitus with arterial hypertension, obesity, and cardiovascular diseases. Hyperglycemia, elevated blood pressure, rapid breathing, and low saturation were more common for these patients. Conclusion: Diabetes mellitus ranks second in the structure of comorbidities in COVID-19 in the south region of Kazakhstan and is characterized by a combination with cardiovascular diseases, arterial hypertension and obesity. In patients with diabetes, COVID-19 is more severe, which affects the length of stay in the hospital, the mortality rate and the need for transfer to the Intensive Care Unit.

comorbidities , COVID-19 , diabetes mellitus , pandemic

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Department of General Immunology, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
City Clinical Infectious Diseases Hospital named after I.Zhekenova, Almaty, Kazakhstan
Department of infectious and tropical diseases, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan

Department of General Immunology
City Clinical Infectious Diseases Hospital named after I.Zhekenova
Department of infectious and tropical diseases

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