Thoracolumbar Interfascial Plane Block in Spinal Surgery: A Systematic Review with Meta-Analysis
Abdildin Y.G. Salamat A. Omarov T. Sultanova M. Krassavina Y. Viderman D.
June 2023Elsevier Inc.
World Neurosurgery
2023#17452 - 61 pp.
Objective: As the thoracolumbar interfascial plane (TLIP) block may be a promising alternative in spinal surgery, there is a need for timely meta-analysis of this methods effectiveness in different medical outcomes. Methods: The meta-analysis of 6 randomized controlled studies on the application of TLIP block in spinal surgery was performed under the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. The primary outcome used for comparison was the mean difference (MD) of pain intensity scores at rest/in motion between patients receiving TLIP block and those receiving no block care. Results: Our analysis favors TLIP block over no block (control group) for pain intensity at rest (MD with 95% confidence interval [CI] is −1.14 [−1.29, −0.99], P value <0.00001, I2 = 99%) and pain intensity in motion (MD with 95% CI is −1.49 [−1.73, −1.24], P value <0.00001, I2 = 99%) on postoperative day 1. Analysis also favors TLIP block in terms of cumulative fentanyl consumption on postoperative day 1 (MD is −166.64 mcg with 95% CI [−204.48, −128.80], P value <0.00001, I2 = 89%), postoperative side effects (risk ratio with 95% CI is 0.63 [0.44, 0.91], P value = 0.01, I2 = 0%), requests for supplementary/rescue analgesia (risk ratio with 95% CI is 0.36 [0.23, 0.49], P value <0.00001, I2 = 0%). The results are statistically significant. Conclusions: The TLIP block reduces postoperative pain intensity, opioid consumption, side effects, and requests for rescue analgesia after spinal surgery more than the no-block alternative.
Meta-analysis , Opioid consumption , Pain intensity , Regional anesthesia , Spinal surgery , Thoracolumbar interfascial plane block
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School of Engineering and Digital Sciences, Nazarbayev University, Astana, Kazakhstan
Nazarbayev University School of Medicine (NUSOM), Astana, Kazakhstan
Department of Anesthesiology and Intensive Care, National Research Oncology Center, Astana, Kazakhstan
School of Engineering and Digital Sciences
Nazarbayev University School of Medicine (NUSOM)
Department of Anesthesiology and Intensive Care
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