Scientific Justification of A Personalized Approach To The Management of Patients with Terminal Renal Failure


Abdigapparkyzy O.S. Zhaksybayevna N.O. Sadykova A. Tazhibayeva K. Moldir A. Kanatzhan K. Bakhtygul B. Darhan A. Elmira B.
29 July 2024Ibn Sina Trust

Bangladesh Journal of Medical Science
2024#23Issue 3851 - 863 pp.

Currently, there is uncertainty about the ideal treatment for recovery and a personalized approach to the management of patients with terminal renal failure.Therefore, a systematic review was conducted over the past 10 years.Network meta-analysis of randomized control trials (RCTS), which compared the prevalence of chronic renal failure (CRF), according to various literature data. AccordingtoWHOitisfrom 50 to 250 peopleper 1 millionpopulationperyear.Active therapy for terminal CRF (hemodialysis, peritoneal dialysis, kidney transplantation) is received in Western Europe by 500-600 patients, in the USA and Japan-1000-1200 patients, while in Kazakhstan-about 100 patients per 1 million population per year. The ten-year probability of survival of patients with terminal CRF in active therapy exceeds 50%, excluding patients with diabetes mellitus.Arterial hypertension remains the most frequent symptom, largely determining the prognosis of patients with CRF. Ten-year survival of patients with CRF in combination with hypertension in hemodialysis is lower than in normotensive patients by 30-50%. Successfully performed a kidney transplant can eliminate the symptoms of chronic renal failure.

end stage , hemodialysis , innovation , peritoneal dialysis , personalized approach , transplantation

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Department of Propaedeutics of internal diseases South Kazakhstan medical academy, Shymkent, Kazakhstan
Department of public health NPJSC “ASTANA MEDICAL UNIVERSITY”, Kazakhstan
Al-Farabi Kazakh National University, Kazakhstan
Al-Farabi Kazakh National University, Al-Farabi Kazakh National University, Asfendiyarov Kazakh National Medical University, Almaty Regional Multidisciplinary Clinic, Kazakhstan
Department for the Development of the Formulary System and Professional Expertise of Medicines and Medical Devices Department for Improving the Medicines Policy of the RSE at the REM “National Scientific Research Center for Healthcare named after Salidat Kairbekova” of the Ministry of Health of the Republic of Kazakhstan, Astana, Kazakhstan
Department of Pediatrics-1, South Kazakhstan medical academy, Shymkent, Kazakhstan
Department of Pediatrics-1, Shymkent, Kazakhstan

Department of Propaedeutics of internal diseases South Kazakhstan medical academy
Department of public health NPJSC “ASTANA MEDICAL UNIVERSITY”
Al-Farabi Kazakh National University
Al-Farabi Kazakh National University
Department for the Development of the Formulary System and Professional Expertise of Medicines and Medical Devices Department for Improving the Medicines Policy of the RSE at the REM “National Scientific Research Center for Healthcare named after Salidat Kairbekova” of the Ministry of Health of the Republic of Kazakhstan
Department of Pediatrics-1
Department of Pediatrics-1

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